[Quantitative assessment of the effect of nitroglycerin on left ventricular function with two-dimensional echocardiography in patients with myocardial infarction]

Zhonghua Nei Ke Za Zhi. 1993 Jan;32(1):21-4.
[Article in Chinese]

Abstract

The effect of sublingual and intravenous nitroglycerin (SLNTG and IVNTG) on left ventricular global and segmental systolic function was quantitatively assessed with two-dimensional echocardiography (2DE) in 28 cases of myocardial infarction (MI), including a group without heart failure of 13 and another group with heart failure of 15. The results showed that after SLNTG and IVNTG the left ventricular end-diastolic and end-systolic volumes were significantly decreased in both groups (P < 0.05-0.001), the left ventricular global systolic function was improved particularly in MI patients with heart failure during IVNTG. The wall motion in the normal and/or hypokinetic segments was enhanced after both SLNTG and IVNTG. It was shown that nitroglycerin could strengthen the left ventricular global systolic function in patients with MI.

MeSH terms

  • Echocardiography
  • Female
  • Heart Failure / etiology
  • Humans
  • Male
  • Middle Aged
  • Myocardial Contraction / drug effects
  • Myocardial Infarction / diagnostic imaging*
  • Myocardial Infarction / drug therapy
  • Myocardial Infarction / physiopathology*
  • Nitroglycerin / pharmacology*
  • Nitroglycerin / therapeutic use
  • Ventricular Function, Left / drug effects*

Substances

  • Nitroglycerin