Sickle cell thalassemia in pregnancy: a case report

J Matern Fetal Med. 1996 Jan-Feb;5(1):28-30. doi: 10.1002/(SICI)1520-6661(199601/02)5:1<28::AID-MFM6>3.0.CO;2-V.

Abstract

A 31-year-old pregnant woman at 20 weeks' gestation was sent to our hospital for fever, anemia, and arthralgias. As she was known to be a double heterozygote for beta-thalassemia and hemoglobin S, a diagnosis of hemolytic anemia caused by sickled red cells vasocclusive crises was made. The patient was submitted to partial exchange transfusion (PET) with a complete recovery. A second PET was performed at 36 weeks' gestation, and elective cesarean section was performed at 37 weeks, with the birth of a normal female neonate.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Anemia, Sickle Cell / complications
  • Anemia, Sickle Cell / diagnosis*
  • Anemia, Sickle Cell / genetics
  • Bilirubin / blood
  • Biomarkers / blood
  • Exchange Transfusion, Whole Blood / standards
  • Female
  • Hemoglobin, Sickle / genetics
  • Hemoglobins / analysis
  • Heterozygote
  • Humans
  • L-Lactate Dehydrogenase / blood
  • Pregnancy
  • Pregnancy Complications, Hematologic / diagnosis*
  • Pregnancy Complications, Hematologic / therapy
  • Pregnancy Outcome
  • beta-Thalassemia / complications
  • beta-Thalassemia / diagnosis*
  • beta-Thalassemia / genetics

Substances

  • Biomarkers
  • Hemoglobin, Sickle
  • Hemoglobins
  • L-Lactate Dehydrogenase
  • Bilirubin