Interleukin-11 (IL-11) and its receptor: biology and potential clinical applications in thrombocytopenic states

Cancer Treat Res. 1995:80:321-40. doi: 10.1007/978-1-4613-1241-3_13.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Base Sequence
  • Bone Marrow Cells
  • Bone Marrow Transplantation
  • Clinical Trials as Topic
  • Erythropoiesis / drug effects
  • Female
  • Fibroblasts / metabolism
  • Gene Expression Regulation / physiology
  • Hematopoiesis / drug effects
  • Hematopoiesis / physiology
  • Humans
  • Immunologic Factors / therapeutic use*
  • Interleukin-11 / genetics
  • Interleukin-11 / pharmacology
  • Interleukin-11 / physiology*
  • Interleukin-11 / therapeutic use
  • Interleukin-11 Receptor alpha Subunit
  • Megakaryocytes / drug effects
  • Mice
  • Models, Biological
  • Molecular Sequence Data
  • Osteoclasts / drug effects
  • Phosphoprotein Phosphatases / genetics
  • Phosphoprotein Phosphatases / metabolism
  • Phosphorylation
  • Primates
  • Protein Processing, Post-Translational
  • Protein-Tyrosine Kinases / metabolism
  • Rats
  • Receptors, Interleukin / chemistry
  • Receptors, Interleukin / drug effects
  • Receptors, Interleukin / genetics
  • Receptors, Interleukin / physiology
  • Receptors, Interleukin-11
  • Signal Transduction / physiology
  • Thrombocytopenia / therapy*
  • Tumor Cells, Cultured / drug effects

Substances

  • IL11RA protein, human
  • Il11ra1 protein, mouse
  • Il11ra1 protein, rat
  • Immunologic Factors
  • Interleukin-11
  • Interleukin-11 Receptor alpha Subunit
  • Receptors, Interleukin
  • Receptors, Interleukin-11
  • Protein-Tyrosine Kinases
  • Phosphoprotein Phosphatases