Spinal myoclonus following intrathecal administration of diatrizoate meglumine

J Neuroimaging. 1996 Oct;6(4):256-8. doi: 10.1111/jon199664256.

Abstract

Life-threatening myoclonus developed in a patient following inadvertent intrathecal usage of 60% diatrizoate meglumine. Rhabdomyolysis and myoglobinuria occurred. The patient was successfully treated with midazolam and vecuronium and complete recovery occurred.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Contrast Media / administration & dosage
  • Contrast Media / adverse effects*
  • Diatrizoate Meglumine / administration & dosage
  • Diatrizoate Meglumine / adverse effects*
  • Humans
  • Hypnotics and Sedatives / therapeutic use
  • Injections, Spinal
  • Male
  • Midazolam / therapeutic use
  • Myoclonus / chemically induced*
  • Myoclonus / drug therapy
  • Myoglobinuria / chemically induced
  • Neuromuscular Nondepolarizing Agents / therapeutic use
  • Rhabdomyolysis / chemically induced
  • Spinal Cord Diseases / chemically induced*
  • Spinal Cord Diseases / drug therapy
  • Vecuronium Bromide / therapeutic use

Substances

  • Contrast Media
  • Hypnotics and Sedatives
  • Neuromuscular Nondepolarizing Agents
  • Diatrizoate Meglumine
  • Vecuronium Bromide
  • Midazolam