Comparison of caudal bupivacaine and diamorphine with caudal bupivacaine alone for repair of hypospadias

Br J Anaesth. 1996 Nov;77(5):586-90. doi: 10.1093/bja/77.5.586.

Abstract

Forty-five boys undergoing repair of hypospadias were allocated randomly to one of two groups. After induction of anaesthesia, 22 patients received 0.25% caudal bupivacaine 0.5 ml kg-1 and diamorphine 30 micrograms kg-1 and the remaining 23 patients received 0.25% caudal bupivacaine 0.5 ml kg-1 alone. Pain scores (Children's Hospital of Eastern Ontario Pain Scale), sedation scores, ventilatory frequency, analgesic requirements and associated side effects were recorded for the first 24 h after operation. The two groups were indistinguishable in age, weight and duration of surgery. There was a statistically significant reduction in early pain scores. There was also a statistically significant increase in the time to first passage of urine in those boys in the diamorphine group who were not catheterized during operation.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Analgesics, Opioid / therapeutic use*
  • Anesthetics, Local / therapeutic use
  • Bupivacaine / therapeutic use
  • Child
  • Child, Preschool
  • Consciousness / drug effects
  • Drug Therapy, Combination
  • Heroin / therapeutic use*
  • Humans
  • Hypospadias / surgery*
  • Infant
  • Injections, Spinal
  • Male
  • Pain, Postoperative / prevention & control*
  • Postoperative Period
  • Respiration / drug effects
  • Urination / drug effects

Substances

  • Analgesics, Opioid
  • Anesthetics, Local
  • Heroin
  • Bupivacaine