MLL cleavage occurs in approximately 5% of de novo acute myeloid leukemia, including in patients analyzed before treatment induction

Blood. 1997 Mar 15;89(6):2224-6.
No abstract available

Publication types

  • Letter
  • Comment

MeSH terms

  • Acute Disease
  • Chromosomes, Human, Pair 11
  • DNA Fragmentation*
  • DNA-Binding Proteins / genetics*
  • Histone-Lysine N-Methyltransferase
  • Humans
  • Leukemia, Myeloid / drug therapy*
  • Leukemia, Myeloid / genetics*
  • Myeloid-Lymphoid Leukemia Protein
  • Proto-Oncogenes*
  • Remission Induction
  • Transcription Factors*

Substances

  • DNA-Binding Proteins
  • KMT2A protein, human
  • Transcription Factors
  • Myeloid-Lymphoid Leukemia Protein
  • Histone-Lysine N-Methyltransferase