Wheelchair propulsion kinetic measurements require the use of custom pushrim force/moment measuring instruments which are not currently commercially available. With the ability to measure pushrim forces and moments has come the development of several dynamic metrics derived for analyzing key aspects of wheelchair propulsion. This paper presents several of the equations used to calculate or derive the primary variables used in the study of wheelchair propulsion biomechanics. The uncertainties for these variables were derived, and then numerically calculated for a current version of the SMARTWheel. The uncertainty results indicate that the SMARTWheel provides data which has better than 5 to 10% uncertainty, depending upon the variable concerned, at the maximum, and during most of the propulsion phase the uncertainty is considerably smaller (i.e., approximately 1%). The uncertainty analysis provides a more complete picture of the attainable accuracy of the SMARTWheel and of the degree of confidence with which the data can be recorded. The derivations and results indicate where improvements in measurement of wheelchair propulsion biomechanical variables are likely to originate. The most efficient approach is to address those variables in the design of the system which make the greatest contribution to the uncertainty. Future research will focus on the point of force application and examination of nonlinear effects.