Abstract
With a view to improving the sensitivity of serological detection of Aspergillus galactomannan (GM), a europium-linked time-resolved fluoroimmunoassay was developed. This method was compared to an enzyme-linked immunosorbent assay using a peroxidase-conjugated detector antibody. No increase in the sensitivity of the detection of GM standards was seen with the europium-based fluoroimmunoassay.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Antigens, Fungal / analysis*
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Aspergillosis / diagnosis*
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Aspergillus / isolation & purification*
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Enzyme-Linked Immunosorbent Assay / methods
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Europium
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Fluorescent Antibody Technique
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Galactose / analogs & derivatives
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Humans
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Mannans / analysis*
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Sensitivity and Specificity
Substances
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Antigens, Fungal
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Mannans
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galactomannan
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Europium
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Galactose