Proton magnetic resonance spectroscopy of fetal lamb brain during hypoxia

Am J Obstet Gynecol. 1998 Sep;179(3 Pt 1):756-7. doi: 10.1016/s0002-9378(98)70077-8.

Abstract

Proton magnetic resonance spectroscopy of fetal lamb brain was performed simultaneously with repeated measurements of fetal arterial oxygen saturation during decrease of oxygen supply. Magnetic resonance spectra displayed the same metabolite peaks as detected in the human fetal brain. Cerebral lactate signals could be detected during fetal hypoxia.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Brain / embryology*
  • Brain / metabolism*
  • Fetal Blood / metabolism
  • Fetal Hypoxia / blood
  • Fetal Hypoxia / diagnosis*
  • Fetal Hypoxia / metabolism*
  • Fetus / metabolism
  • Lactic Acid / blood
  • Lactic Acid / metabolism
  • Magnetic Resonance Spectroscopy
  • Oxygen / blood
  • Oxygen / metabolism
  • Sheep / embryology

Substances

  • Lactic Acid
  • Oxygen