Abstract
Integration of mycobacteriophage L5 requires the mycobacterial integration host factor (mIHF) in vitro. mIHF is a 105-residue heat-stable polypeptide that is not obviously related to HU or any other small DNA-binding proteins. mIHF is most abundant just prior to entry into stationary phase and is essential for the viability of Mycobacterium smegmatis.
Publication types
-
Comparative Study
-
Research Support, U.S. Gov't, P.H.S.
MeSH terms
-
Alleles
-
Bacterial Proteins / genetics*
-
Base Sequence
-
Cell Division
-
Genes, Bacterial*
-
Integration Host Factors
-
Molecular Sequence Data
-
Mutagenesis
-
Mycobacteriophages / genetics
-
Mycobacterium smegmatis / genetics*
-
Mycobacterium smegmatis / growth & development
-
Mycobacterium tuberculosis / genetics
-
Sequence Homology, Nucleic Acid
Substances
-
Bacterial Proteins
-
Integration Host Factors