Rupture of ectopic pregnancy after medical therapy with methotrexate: a case series

J Emerg Med. 1998 Nov-Dec;16(6):857-60. doi: 10.1016/s0736-4679(98)00098-5.

Abstract

Medical treatment of ectopic pregnancy with methotrexate has become the standard of care in many areas of the U.S. Rupture of ectopic pregnancy after medical treatment presents a diagnostic challenge to the Emergency Physician. We review a series of 11 patients with ectopic pregnancy treated with methotrexate who then required surgical treatment for rupture.

Publication types

  • Clinical Trial

MeSH terms

  • Abortifacient Agents, Nonsteroidal / adverse effects*
  • Abortifacient Agents, Nonsteroidal / therapeutic use
  • Adolescent
  • Adult
  • Emergency Service, Hospital
  • Fallopian Tube Diseases / etiology*
  • Fallopian Tube Diseases / surgery
  • Female
  • Humans
  • Laparotomy
  • Methotrexate / adverse effects*
  • Methotrexate / therapeutic use
  • Pregnancy
  • Pregnancy, Tubal / drug therapy*
  • Prognosis
  • Registries
  • Rupture, Spontaneous / etiology
  • Rupture, Spontaneous / surgery
  • Treatment Outcome

Substances

  • Abortifacient Agents, Nonsteroidal
  • Methotrexate