Ijzerman AP - Search Results

1

Stochastic multidimensional hypercubes and inverse agonism.

Milligan G, Ijzerman AP. Milligan G, et al. Among authors: ijzerman ap. Trends Pharmacol Sci. 2000 Oct;21(10):362-3. doi: 10.1016/s0165-6147(00)01540-6. Trends Pharmacol Sci. 2000. PMID: 11203388 No abstract available.

2

Allosteric modulation and constitutive activity of fusion proteins between the adenosine A1 receptor and different 351Cys-mutated Gi alpha-subunits.

Klaasse E, de Ligt RA, Roerink SF, Lorenzen A, Milligan G, Leurs R, IJzerman AP. Klaasse E, et al. Among authors: ijzerman ap. Eur J Pharmacol. 2004 Sep 19;499(1-2):91-8. doi: 10.1016/j.ejphar.2004.07.108. Eur J Pharmacol. 2004. PMID: 15363955

3

Adenosine and ATP: from receptor structure to clinical applications.

Kennedy C, IJzerman A. Kennedy C, et al. Trends Pharmacol Sci. 1994 Sep;15(9):311-2. doi: 10.1016/0165-6147(94)90018-3. Trends Pharmacol Sci. 1994. PMID: 7992379 No abstract available.

4

Recent developments in constitutive receptor activity and inverse agonism, and their potential for GPCR drug discovery.

Bond RA, Ijzerman AP. Bond RA, et al. Among authors: ijzerman ap. Trends Pharmacol Sci. 2006 Feb;27(2):92-6. doi: 10.1016/j.tips.2005.12.007. Epub 2006 Jan 6. Trends Pharmacol Sci. 2006. PMID: 16406086 Review.

5

Principles of agonism: undressing efficacy.

Schwartz TW, IJzerman AP. Schwartz TW, et al. Among authors: ijzerman ap. Trends Pharmacol Sci. 1998 Nov;19(11):433-6. doi: 10.1016/s0165-6147(98)01262-0. Trends Pharmacol Sci. 1998. PMID: 9850604 No abstract available.

6

Synthesis and biological evaluation of disubstituted N6-cyclopentyladenine analogues: the search for a neutral antagonist with high affinity for the adenosine A1 receptor.

de Ligt RA, van der Klein PA, von Frijtag Drabbe Künzel JK, Lorenzen A, Ait El Maate F, Fujikawa S, van Westhoven R, van den Hoven T, Brussee J, IJzerman AP. de Ligt RA, et al. Among authors: ijzerman ap. Bioorg Med Chem. 2004 Jan 2;12(1):139-49. doi: 10.1016/j.bmc.2003.10.023. Bioorg Med Chem. 2004. PMID: 14697779

7

A "locked-on," constitutively active mutant of the adenosine A1 receptor.

de Ligt RA, Rivkees SA, Lorenzen A, Leurs R, IJzerman AP. de Ligt RA, et al. Among authors: ijzerman ap. Eur J Pharmacol. 2005 Mar 7;510(1-2):1-8. doi: 10.1016/j.ejphar.2005.01.007. Eur J Pharmacol. 2005. PMID: 15740718

8

Allosteric modulators affect the internalization of human adenosine A1 receptors.

Klaasse EC, van den Hout G, Roerink SF, de Grip WJ, Ijzerman AP, Beukers MW. Klaasse EC, et al. Among authors: ijzerman ap. Eur J Pharmacol. 2005 Oct 17;522(1-3):1-8. doi: 10.1016/j.ejphar.2005.08.052. Epub 2005 Oct 7. Eur J Pharmacol. 2005. PMID: 16214128

9

Intrinsic activity at adenosine A1 receptors: partial and inverse agonism.

de Ligt RA, IJzerman AP. de Ligt RA, et al. Among authors: ijzerman ap. Curr Pharm Des. 2002;8(26):2333-44. doi: 10.2174/1381612023392874. Curr Pharm Des. 2002. PMID: 12369948 Review.

10

Effects of the adenosine A1 receptor allosteric modulators PD 81,723 and LUF 5484 on the striatal acetylcholine release.

Bueters TJ, van Helden HP, Danhof M, IJzerman AP. Bueters TJ, et al. Among authors: ijzerman ap. Eur J Pharmacol. 2002 Nov 15;454(2-3):177-82. doi: 10.1016/s0014-2999(02)02494-9. Eur J Pharmacol. 2002. PMID: 12421644

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