Wright CV - Search Results

1

Reduction in pancreatic transcription factor PDX-1 impairs glucose-stimulated insulin secretion.

Brissova M, Shiota M, Nicholson WE, Gannon M, Knobel SM, Piston DW, Wright CV, Powers AC. Brissova M, et al. Among authors: wright cv. J Biol Chem. 2002 Mar 29;277(13):11225-32. doi: 10.1074/jbc.M111272200. Epub 2002 Jan 7. J Biol Chem. 2002. PMID: 11781323 Free article.

2

Reduced PDX-1 expression impairs islet response to insulin resistance and worsens glucose homeostasis.

Brissova M, Blaha M, Spear C, Nicholson W, Radhika A, Shiota M, Charron MJ, Wright CV, Powers AC. Brissova M, et al. Among authors: wright cv. Am J Physiol Endocrinol Metab. 2005 Apr;288(4):E707-14. doi: 10.1152/ajpendo.00252.2004. Epub 2004 Nov 23. Am J Physiol Endocrinol Metab. 2005. PMID: 15562255 Free article.

3

Pancreatic beta cell-specific transcription of the pdx-1 gene. The role of conserved upstream control regions and their hepatic nuclear factor 3beta sites.

Gerrish K, Gannon M, Shih D, Henderson E, Stoffel M, Wright CV, Stein R. Gerrish K, et al. Among authors: wright cv. J Biol Chem. 2000 Feb 4;275(5):3485-92. doi: 10.1074/jbc.275.5.3485. J Biol Chem. 2000. PMID: 10652343 Free article.

4

Conserved sequences in a tissue-specific regulatory region of the pdx-1 gene mediate transcription in Pancreatic beta cells: role for hepatocyte nuclear factor 3 beta and Pax6.

Samaras SE, Cissell MA, Gerrish K, Wright CV, Gannon M, Stein R. Samaras SE, et al. Among authors: wright cv. Mol Cell Biol. 2002 Jul;22(13):4702-13. doi: 10.1128/MCB.22.13.4702-4713.2002. Mol Cell Biol. 2002. PMID: 12052878 Free PMC article.

5

Efficient recombination in pancreatic islets by a tamoxifen-inducible Cre-recombinase.

Zhang H, Fujitani Y, Wright CV, Gannon M. Zhang H, et al. Among authors: wright cv. Genesis. 2005 Jul;42(3):210-7. doi: 10.1002/gene.20137. Genesis. 2005. PMID: 15986486

6

Targeted deletion of a cis-regulatory region reveals differential gene dosage requirements for Pdx1 in foregut organ differentiation and pancreas formation.

Fujitani Y, Fujitani S, Boyer DF, Gannon M, Kawaguchi Y, Ray M, Shiota M, Stein RW, Magnuson MA, Wright CV. Fujitani Y, et al. Among authors: wright cv. Genes Dev. 2006 Jan 15;20(2):253-66. doi: 10.1101/gad.1360106. Genes Dev. 2006. PMID: 16418487 Free PMC article.

7

Complementation rescue of Pdx1 null phenotype demonstrates distinct roles of proximal and distal cis-regulatory sequences in pancreatic and duodenal expression.

Boyer DF, Fujitani Y, Gannon M, Powers AC, Stein RW, Wright CV. Boyer DF, et al. Among authors: wright cv. Dev Biol. 2006 Oct 15;298(2):616-31. doi: 10.1016/j.ydbio.2006.07.020. Epub 2006 Jul 26. Dev Biol. 2006. PMID: 16962573 Free article.

8

pdx-1 function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis.

Gannon M, Ables ET, Crawford L, Lowe D, Offield MF, Magnuson MA, Wright CV. Gannon M, et al. Among authors: wright cv. Dev Biol. 2008 Feb 15;314(2):406-17. doi: 10.1016/j.ydbio.2007.10.038. Epub 2007 Nov 4. Dev Biol. 2008. PMID: 18155690 Free PMC article.

9

Inactivating the permanent neonatal diabetes gene Mnx1 switches insulin-producing β-cells to a δ-like fate and reveals a facultative proliferative capacity in aged β-cells.

Pan FC, Brissova M, Powers AC, Pfaff S, Wright CV. Pan FC, et al. Among authors: wright cv. Development. 2015 Nov 1;142(21):3637-48. doi: 10.1242/dev.126011. Development. 2015. PMID: 26534984 Free PMC article.

10

Threshold-Dependent Cooperativity of Pdx1 and Oc1 in Pancreatic Progenitors Establishes Competency for Endocrine Differentiation and β-Cell Function.

Henley KD, Stanescu DE, Kropp PA, Wright CVE, Won KJ, Stoffers DA, Gannon M. Henley KD, et al. Cell Rep. 2016 Jun 21;15(12):2637-2650. doi: 10.1016/j.celrep.2016.05.040. Epub 2016 Jun 9. Cell Rep. 2016. PMID: 27292642 Free PMC article.

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