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Selective STING Activation in Intratumoral Myeloid Cells via CCR2-Directed Antibody-Drug Conjugate TAK-500.
Appleman VA, Matsuda A, Ganno ML, Zhang DM, Rosentrater E, Maldonado Lopez AE, Porciuncula A, Hatten T, Christensen CL, Merrigan SA, Lee HM, Lee MY, Wang CI, Dong L, Huang J, Iartchouk N, Wang J, Xu H, Yoneyama T, Piatkov KI, Haridas S, Harbison CE, Gregory RC, Parent A, Lineberry N, Arendt C, Schalper KA, Abu-Yousif AO. Appleman VA, et al. Among authors: christensen cl. Cancer Immunol Res. 2025 May 2;13(5):661-679. doi: 10.1158/2326-6066.CIR-24-0103. Cancer Immunol Res. 2025. PMID: 39918395 Free PMC article.
Acquired Cross-Resistance in Small Cell Lung Cancer due to Extrachromosomal DNA Amplification of MYC Paralogs.
Pal Choudhuri S, Girard L, Lim JYS, Wise JF, Freitas B, Yang D, Wong E, Hamilton S, Chien VD, Kim YJ, Gilbreath C, Zhong J, Phat S, Myers DT, Christensen CL, Mazloom-Farsibaf H, Stanzione M, Wong KK, Hung YP, Farago AF, Meador CB, Dyson NJ, Lawrence MS, Wu S, Drapkin BJ. Pal Choudhuri S, et al. Among authors: christensen cl. Cancer Discov. 2024 May 1;14(5):804-827. doi: 10.1158/2159-8290.CD-23-0656. Cancer Discov. 2024. PMID: 38386926 Free PMC article.
Base editing corrects the common Salla disease SLC17A5 c.115C>T variant.
Harb JF, Christensen CL, Kan SH, Rha AK, Andrade-Heckman P, Pollard L, Steet R, Huang JY, Wang RY. Harb JF, et al. Among authors: christensen cl. Mol Ther Nucleic Acids. 2023 Aug 26;34:102022. doi: 10.1016/j.omtn.2023.08.024. eCollection 2023 Dec 12. Mol Ther Nucleic Acids. 2023. PMID: 37727271 Free PMC article.
Acquired Cross-resistance in Small Cell Lung Cancer due to Extrachromosomal DNA Amplification of MYC paralogs.
Choudhuri SP, Girard L, Lim JYS, Wise JF, Freitas B, Yang D, Wong E, Hamilton S, Chien VD, Gilbreath C, Zhong J, Phat S, Myers DT, Christensen CL, Stanzione M, Wong KK, Farago AF, Meador CB, Dyson NJ, Lawrence MS, Wu S, Drapkin BJ. Choudhuri SP, et al. Among authors: christensen cl. bioRxiv [Preprint]. 2023 Jun 28:2023.06.23.546278. doi: 10.1101/2023.06.23.546278. bioRxiv. 2023. Update in: Cancer Discov. 2024 May 1;14(5):804-827. doi: 10.1158/2159-8290.CD-23-0656. PMID: 37425738 Free PMC article. Updated. Preprint.
73 results