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T-1249 retains potent antiretroviral activity in patients who had experienced virological failure while on an enfuvirtide-containing treatment regimen.
Lalezari JP, Bellos NC, Sathasivam K, Richmond GJ, Cohen CJ, Myers RA Jr, Henry DH, Raskino C, Melby T, Murchison H, Zhang Y, Spence R, Greenberg ML, Demasi RA, Miralles GD; T1249-102 Study Group. Lalezari JP, et al. Among authors: miralles gd. J Infect Dis. 2005 Apr 1;191(7):1155-63. doi: 10.1086/427993. Epub 2005 Feb 22. J Infect Dis. 2005. PMID: 15747252 Clinical Trial.
Changes in CD4+ T-cell differentiation phenotype during structured treatment interruption in patients with chronic HIV-1 infection.
Alexander TH, Ortiz GM, Wellons MF, Allen A, Grace EJ 2nd, Schweighardt B, Brancato J, Sandberg JK, Furlan SN, Miralles GD, Nixon DF, Bartlett JA. Alexander TH, et al. Among authors: miralles gd. J Acquir Immune Defic Syndr. 2003 Dec 15;34(5):475-81. doi: 10.1097/00126334-200312150-00005. J Acquir Immune Defic Syndr. 2003. PMID: 14657757
Structured antiretroviral treatment interruptions in chronically HIV-1-infected subjects.
Ortiz GM, Wellons M, Brancato J, Vo HT, Zinn RL, Clarkson DE, Van Loon K, Bonhoeffer S, Miralles GD, Montefiori D, Bartlett JA, Nixon DF. Ortiz GM, et al. Among authors: miralles gd. Proc Natl Acad Sci U S A. 2001 Nov 6;98(23):13288-93. doi: 10.1073/pnas.221452198. Epub 2001 Oct 30. Proc Natl Acad Sci U S A. 2001. PMID: 11687611 Free PMC article. Clinical Trial.
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