Varella-Garcia M - Search Results

1

Epidermal growth factor receptor and cyclin D1 are independently amplified and overexpressed in esophageal squamous cell carcinoma.

Sunpaweravong P, Sunpaweravong S, Puttawibul P, Mitarnun W, Zeng C, Barón AE, Franklin W, Said S, Varella-Garcia M. Sunpaweravong P, et al. J Cancer Res Clin Oncol. 2005 Feb;131(2):111-9. doi: 10.1007/s00432-004-0610-7. Epub 2004 Oct 19. J Cancer Res Clin Oncol. 2005. PMID: 15672286

2

Epidermal growth factor receptor in non-small-cell lung carcinomas: correlation between gene copy number and protein expression and impact on prognosis.

Hirsch FR, Varella-Garcia M, Bunn PA Jr, Di Maria MV, Veve R, Bremmes RM, Barón AE, Zeng C, Franklin WA. Hirsch FR, et al. J Clin Oncol. 2003 Oct 15;21(20):3798-807. doi: 10.1200/JCO.2003.11.069. Epub 2003 Sep 2. J Clin Oncol. 2003. PMID: 12953099

3

Epidermal growth factor receptor messenger RNA expression, gene dosage, and gefitinib sensitivity in non-small cell lung cancer.

Dziadziuszko R, Witta SE, Cappuzzo F, Park S, Tanaka K, Danenberg PV, Barón AE, Crino L, Franklin WA, Bunn PA Jr, Varella-Garcia M, Danenberg KD, Hirsch FR. Dziadziuszko R, et al. Clin Cancer Res. 2006 May 15;12(10):3078-84. doi: 10.1158/1078-0432.CCR-06-0106. Clin Cancer Res. 2006. PMID: 16707605

4

Antitumor activity of the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor gefitinib (ZD1839, Iressa) in non-small cell lung cancer cell lines correlates with gene copy number and EGFR mutations but not EGFR protein levels.

Helfrich BA, Raben D, Varella-Garcia M, Gustafson D, Chan DC, Bemis L, Coldren C, Barón A, Zeng C, Franklin WA, Hirsch FR, Gazdar A, Minna J, Bunn PA Jr. Helfrich BA, et al. Clin Cancer Res. 2006 Dec 1;12(23):7117-25. doi: 10.1158/1078-0432.CCR-06-0760. Clin Cancer Res. 2006. PMID: 17145836

5

Expression of Her-2/neu in human lung cancer cell lines by immunohistochemistry and fluorescence in situ hybridization and its relationship to in vitro cytotoxicity by trastuzumab and chemotherapeutic agents.

Bunn PA Jr, Helfrich B, Soriano AF, Franklin WA, Varella-Garcia M, Hirsch FR, Baron A, Zeng C, Chan DC. Bunn PA Jr, et al. Clin Cancer Res. 2001 Oct;7(10):3239-50. Clin Cancer Res. 2001. PMID: 11595720

6

Evaluation of HER-2/neu gene amplification and protein expression in non-small cell lung carcinomas.

Hirsch FR, Varella-Garcia M, Franklin WA, Veve R, Chen L, Helfrich B, Zeng C, Baron A, Bunn PA Jr. Hirsch FR, et al. Br J Cancer. 2002 May 6;86(9):1449-56. doi: 10.1038/sj.bjc.6600286. Br J Cancer. 2002. PMID: 11986780 Free PMC article.

7

Epidermal growth factor family of receptors in preneoplasia and lung cancer: perspectives for targeted therapies.

Hirsch FR, Scagliotti GV, Langer CJ, Varella-Garcia M, Franklin WA. Hirsch FR, et al. Lung Cancer. 2003 Aug;41 Suppl 1:S29-42. doi: 10.1016/s0169-5002(03)00137-5. Lung Cancer. 2003. PMID: 12867060 Review.

8

Increased HER2 gene copy number is associated with response to gefitinib therapy in epidermal growth factor receptor-positive non-small-cell lung cancer patients.

Cappuzzo F, Varella-Garcia M, Shigematsu H, Domenichini I, Bartolini S, Ceresoli GL, Rossi E, Ludovini V, Gregorc V, Toschi L, Franklin WA, Crino L, Gazdar AF, Bunn PA Jr, Hirsch FR. Cappuzzo F, et al. J Clin Oncol. 2005 Aug 1;23(22):5007-18. doi: 10.1200/JCO.2005.09.111. J Clin Oncol. 2005. PMID: 16051952

9

Biological markers for non-small cell lung cancer patient selection for epidermal growth factor receptor tyrosine kinase inhibitor therapy.

Bunn PA Jr, Dziadziuszko R, Varella-Garcia M, Franklin WA, Witta SE, Kelly K, Hirsch FR. Bunn PA Jr, et al. Clin Cancer Res. 2006 Jun 15;12(12):3652-6. doi: 10.1158/1078-0432.CCR-06-0261. Clin Cancer Res. 2006. PMID: 16778092 Review. No abstract available.

10

First-generation epidermal growth factor receptor inhibitors in non-small cell lung cancer: clinical impact of the epidermal growth factor receptor fluorescence in situ hybridization assay.

Hirsch FR, Dziadziuszko R, Varella-Garcia M, Franklin WA, Gandara DR, Bunn PA Jr. Hirsch FR, et al. J Thorac Oncol. 2008 Jun;3(6 Suppl 2):S138-42. doi: 10.1097/JTO.0b013e318174e922. J Thorac Oncol. 2008. PMID: 18520298 Free article. Review.

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