Flory C - Search Results

1

Oral treatment with PD-0200347, an alpha2delta ligand, reduces the development of experimental osteoarthritis by inhibiting metalloproteinases and inducible nitric oxide synthase gene expression and synthesis in cartilage chondrocytes.

Boileau C, Martel-Pelletier J, Brunet J, Tardif G, Schrier D, Flory C, El-Kattan A, Boily M, Pelletier JP. Boileau C, et al. Among authors: flory c. Arthritis Rheum. 2005 Feb;52(2):488-500. doi: 10.1002/art.20809. Arthritis Rheum. 2005. PMID: 15693013

2

PD-0200347, an alpha2delta ligand of the voltage gated calcium channel, inhibits in vivo activation of the Erk1/2 pathway in osteoarthritic chondrocytes: a PKCalpha dependent effect.

Boileau C, Martel-Pelletier J, Brunet J, Schrier D, Flory C, Boily M, Pelletier JP. Boileau C, et al. Among authors: flory c. Ann Rheum Dis. 2006 May;65(5):573-80. doi: 10.1136/ard.2005.041855. Epub 2005 Oct 25. Ann Rheum Dis. 2006. PMID: 16249226 Free PMC article.

3

In vivo selective inhibition of mitogen-activated protein kinase kinase 1/2 in rabbit experimental osteoarthritis is associated with a reduction in the development of structural changes.

Pelletier JP, Fernandes JC, Brunet J, Moldovan F, Schrier D, Flory C, Martel-Pelletier J. Pelletier JP, et al. Among authors: flory c. Arthritis Rheum. 2003 Jun;48(6):1582-93. doi: 10.1002/art.11014. Arthritis Rheum. 2003. PMID: 12794826

4

The effects of the phospholipase A2 inhibitor, manoalide, on cartilage degradation, stromelysin expression, and synovial fluid cell count induced by intraarticular injection of human recombinant interleukin-1 alpha in the rabbit.

Schrier DJ, Flory CM, Finkel M, Kuchera SL, Lesch ME, Jacobson PB. Schrier DJ, et al. Among authors: flory cm. Arthritis Rheum. 1996 Aug;39(8):1292-9. doi: 10.1002/art.1780390805. Arthritis Rheum. 1996. PMID: 8702436

5

Central role of the MEK/ERK MAP kinase pathway in a mouse model of rheumatoid arthritis: potential proinflammatory mechanisms.

Thiel MJ, Schaefer CJ, Lesch ME, Mobley JL, Dudley DT, Tecle H, Barrett SD, Schrier DJ, Flory CM. Thiel MJ, et al. Arthritis Rheum. 2007 Oct;56(10):3347-57. doi: 10.1002/art.22869. Arthritis Rheum. 2007. PMID: 17907188

6

Ribozymes as tools for therapeutic target validation in arthritis.

Jarvis TC, Bouhana KS, Lesch ME, Brown SA, Parry TJ, Schrier DJ, Hunt SW 3rd, Pavco PA, Flory CM. Jarvis TC, et al. Among authors: flory cm. J Immunol. 2000 Jul 1;165(1):493-8. doi: 10.4049/jimmunol.165.1.493. J Immunol. 2000. PMID: 10861088 Free article.

7

Nuclease-resistant ribozymes decrease stromelysin mRNA levels in rabbit synovium following exogenous delivery to the knee joint.

Flory CM, Pavco PA, Jarvis TC, Lesch ME, Wincott FE, Beigelman L, Hunt SW 3rd, Schrier DJ. Flory CM, et al. Proc Natl Acad Sci U S A. 1996 Jan 23;93(2):754-8. doi: 10.1073/pnas.93.2.754. Proc Natl Acad Sci U S A. 1996. PMID: 8570629 Free PMC article.

8

Expression of lung vascular and airway ICAM-1 after exposure to bacterial lipopolysaccharide.

Beck-Schimmer B, Schimmer RC, Warner RL, Schmal H, Nordblom G, Flory CM, Lesch ME, Friedl HP, Schrier DJ, Ward PA. Beck-Schimmer B, et al. Among authors: flory cm. Am J Respir Cell Mol Biol. 1997 Sep;17(3):344-52. doi: 10.1165/ajrcmb.17.3.2861. Am J Respir Cell Mol Biol. 1997. PMID: 9308921

9

Role of chemokines and cytokines in a reactivation model of arthritis in rats induced by injection with streptococcal cell walls.

Schrier DJ, Schimmer RC, Flory CM, Tung DK, Ward PA. Schrier DJ, et al. Among authors: flory cm. J Leukoc Biol. 1998 Mar;63(3):359-63. doi: 10.1002/jlb.63.3.359. J Leukoc Biol. 1998. PMID: 9500524 Free article.

10

Streptococcal cell wall-induced arthritis: requirements for IL-4, IL-10, IFN-gamma, and monocyte chemoattractant protein-1.

Schimmer RC, Schrier DJ, Flory CM, Laemont KD, Tung D, Metz AL, Friedl HP, Conroy MC, Warren JS, Beck B, Ward PA. Schimmer RC, et al. Among authors: flory cm. J Immunol. 1998 Feb 1;160(3):1466-71. J Immunol. 1998. PMID: 9570568

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