Gordon JC - Search Results

1

Synthesis and biodistribution of radiolabeled alpha 7 nicotinic acetylcholine receptor ligands.

Pomper MG, Phillips E, Fan H, McCarthy DJ, Keith RA, Gordon JC, Scheffel U, Dannals RF, Musachio JL. Pomper MG, et al. Among authors: gordon jc. J Nucl Med. 2005 Feb;46(2):326-34. J Nucl Med. 2005. PMID: 15695794 Free article.

2

In vitro binding characteristics of [3H]AZ11637326, a novel alpha7-selective neuronal nicotinic receptor agonist radioligand.

Gordon JC, Phillips E, Gurley DA, Heys JR, Lazor LA, Barthlow HG, Mallamaci MA, Keith RA. Gordon JC, et al. Eur J Pharmacol. 2010 Oct 25;645(1-3):63-9. doi: 10.1016/j.ejphar.2010.07.035. Epub 2010 Jul 30. Eur J Pharmacol. 2010. PMID: 20674564

3

(-)-Spiro[1-azabicyclo[2.2.2]octane-3,5'-oxazolidin-2'-one], a conformationally restricted analogue of acetylcholine, is a highly selective full agonist at the alpha 7 nicotinic acetylcholine receptor.

Mullen G, Napier J, Balestra M, DeCory T, Hale G, Macor J, Mack R, Loch J 3rd, Wu E, Kover A, Verhoest P, Sampognaro A, Phillips E, Zhu Y, Murray R, Griffith R, Blosser J, Gurley D, Machulskis A, Zongrone J, Rosen A, Gordon J. Mullen G, et al. J Med Chem. 2000 Nov 2;43(22):4045-50. doi: 10.1021/jm000249r. J Med Chem. 2000. PMID: 11063601

4

Pre-clinical validation of a novel alpha-7 nicotinic receptor radiotracer, [(3)H]AZ11637326: target localization, biodistribution and ligand occupancy in the rat brain.

Maier DL, Hill G, Ding M, Tuke D, Einstein E, Gurley D, Gordon JC, Bock MJ, Smith JS, Bialecki R, Eisman M, Elmore CS, Werkheiser JL. Maier DL, et al. Among authors: gordon jc. Neuropharmacology. 2011 Jul-Aug;61(1-2):161-71. doi: 10.1016/j.neuropharm.2011.03.024. Epub 2011 Apr 7. Neuropharmacology. 2011. PMID: 21497612

5

The 5-HT3 antagonist tropisetron (ICS 205-930) is a potent and selective alpha7 nicotinic receptor partial agonist.

Macor JE, Gurley D, Lanthorn T, Loch J, Mack RA, Mullen G, Tran O, Wright N, Gordon JC. Macor JE, et al. Among authors: gordon jc. Bioorg Med Chem Lett. 2001 Feb 12;11(3):319-21. doi: 10.1016/s0960-894x(00)00670-3. Bioorg Med Chem Lett. 2001. PMID: 11212100

6

AR-R17779, and alpha7 nicotinic agonist, improves learning and memory in rats.

Levin ED, Bettegowda C, Blosser J, Gordon J. Levin ED, et al. Behav Pharmacol. 1999 Nov;10(6-7):675-80. doi: 10.1097/00008877-199911000-00014. Behav Pharmacol. 1999. PMID: 10780509

7

Selective alpha7 nicotinic receptor activation by AZD0328 enhances cortical dopamine release and improves learning and attentional processes.

Sydserff S, Sutton EJ, Song D, Quirk MC, Maciag C, Li C, Jonak G, Gurley D, Gordon JC, Christian EP, Doherty JJ, Hudzik T, Johnson E, Mrzljak L, Piser T, Smagin GN, Wang Y, Widzowski D, Smith JS. Sydserff S, et al. Among authors: gordon jc. Biochem Pharmacol. 2009 Oct 1;78(7):880-8. doi: 10.1016/j.bcp.2009.07.005. Epub 2009 Jul 16. Biochem Pharmacol. 2009. PMID: 19615981

8

SAR development of a series of 8-azabicyclo[3.2.1]octan-3-yloxy-benzamides as kappa opioid receptor antagonists. Part 2.

Brugel TA, Smith RW, Balestra M, Becker C, Daniels T, Koether GM, Throner SR, Panko LM, Brown DG, Liu R, Gordon J, Peters MF. Brugel TA, et al. Bioorg Med Chem Lett. 2010 Sep 15;20(18):5405-10. doi: 10.1016/j.bmcl.2010.07.112. Epub 2010 Aug 3. Bioorg Med Chem Lett. 2010. PMID: 20719509

9

Historical account of dinitrogen-bridged diiron complex synthesis using a commercial tripodal ligand.

Smythe NC, Mondal J, Duque JG, Feller RK, Flores M, Gordon JC, Henson NJ, Paz-Pasternak M, Rein FN, Scott BL, Taylor RD, Trovitch RJ. Smythe NC, et al. Among authors: gordon jc. Chem Commun (Camb). 2025 Jul 1;61(54):9908-9911. doi: 10.1039/d5cc02058a. Chem Commun (Camb). 2025. PMID: 40474851

10

Novel 5-HT₇ receptor antagonists modulate intestinal immune responses and reduce severity of colitis.

Kwon YH, Blass BE, Wang H, Grondin JA, Banskota S, Korzekwa K, Ye M, Gordon JC, Colussi D, Blattner KM, Canney DJ, Khan WI. Kwon YH, et al. Among authors: gordon jc. Am J Physiol Gastrointest Liver Physiol. 2024 Jul 1;327(1):G57-G69. doi: 10.1152/ajpgi.00299.2023. Epub 2024 May 7. Am J Physiol Gastrointest Liver Physiol. 2024. PMID: 38713616 Free PMC article.

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