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A dose escalating, placebo controlled, double blind, single dose and multidose, safety and tolerability study of fontolizumab, a humanised anti-interferon gamma antibody, in patients with moderate to severe Crohn's disease.
Reinisch W, Hommes DW, Van Assche G, Colombel JF, Gendre JP, Oldenburg B, Teml A, Geboes K, Ding H, Zhang L, Tang M, Cheng M, van Deventer SJ, Rutgeerts P, Pearce T. Reinisch W, et al. Among authors: van assche g, van deventer sj. Gut. 2006 Aug;55(8):1138-44. doi: 10.1136/gut.2005.079434. Epub 2006 Feb 21. Gut. 2006. PMID: 16492717 Free PMC article. Clinical Trial.
Management of acute severe ulcerative colitis.
Van Assche G, Vermeire S, Rutgeerts P. Van Assche G, et al. Gut. 2011 Jan;60(1):130-3. doi: 10.1136/gut.2009.192765. Epub 2010 Oct 28. Gut. 2011. PMID: 21030524 Review.
Daclizumab, a humanised monoclonal antibody to the interleukin 2 receptor (CD25), for the treatment of moderately to severely active ulcerative colitis: a randomised, double blind, placebo controlled, dose ranging trial.
Van Assche G, Sandborn WJ, Feagan BG, Salzberg BA, Silvers D, Monroe PS, Pandak WM, Anderson FH, Valentine JF, Wild GE, Geenen DJ, Sprague R, Targan SR, Rutgeerts P, Vexler V, Young D, Shames RS. Van Assche G, et al. Gut. 2006 Nov;55(11):1568-74. doi: 10.1136/gut.2005.089854. Epub 2006 Apr 7. Gut. 2006. PMID: 16603634 Free PMC article. Clinical Trial.
Anti-TNF agents in Crohn's disease.
Van Assche G, Rutgeerts P. Van Assche G, et al. Expert Opin Investig Drugs. 2000 Jan;9(1):103-11. doi: 10.1517/13543784.9.1.103. Expert Opin Investig Drugs. 2000. PMID: 11060664 Review.
399 results