Link DC - Search Results

1

Distinct patterns of mutations occurring in de novo AML versus AML arising in the setting of severe congenital neutropenia.

Link DC, Kunter G, Kasai Y, Zhao Y, Miner T, McLellan MD, Ries RE, Kapur D, Nagarajan R, Dale DC, Bolyard AA, Boxer LA, Welte K, Zeidler C, Donadieu J, Bellanné-Chantelot C, Vardiman JW, Caligiuri MA, Bloomfield CD, DiPersio JF, Tomasson MH, Graubert TA, Westervelt P, Watson M, Shannon W, Baty J, Mardis ER, Wilson RK, Ley TJ. Link DC, et al. Blood. 2007 Sep 1;110(5):1648-55. doi: 10.1182/blood-2007-03-081216. Epub 2007 May 9. Blood. 2007. PMID: 17494858 Free PMC article. Clinical Trial.

2

Characterization of the 5' untranslated region of the human c-fgr gene and identification of the major myelomonocytic c-fgr promoter.

Link DC, Gutkind SJ, Robbins KC, Ley TJ. Link DC, et al. Oncogene. 1992 May;7(5):877-84. Oncogene. 1992. PMID: 1373875

3

1,25-Dihydroxyvitamin D3 induces monocytic differentiation of the PLB-985 leukemic line and promotes c-fgr mRNA expression.

Perkins SL, Link DC, Kling S, Ley TJ, Teitelbaum SL. Perkins SL, et al. Among authors: link dc. J Leukoc Biol. 1991 Nov;50(5):427-33. doi: 10.1002/jlb.50.5.427. J Leukoc Biol. 1991. PMID: 1660912

4

The proto-oncogene c-fgr is expressed in normal mantle zone B lymphocytes and is developmentally regulated during myelomonocytic differentiation in vivo.

Link DC, Zutter M. Link DC, et al. Blood. 1995 Jan 15;85(2):472-9. Blood. 1995. PMID: 7812001 Free article.

5

Suppression of apoptosis during cytokine deprivation of 32D cells is not sufficient to induce complete granulocytic differentiation.

Rodel JE, Link DC. Rodel JE, et al. Among authors: link dc. Blood. 1996 Feb 1;87(3):858-64. Blood. 1996. PMID: 8562953 Free article.

6

The granulocyte colony-stimulating factor receptor is required for the mobilization of murine hematopoietic progenitors into peripheral blood by cyclophosphamide or interleukin-8 but not flt-3 ligand.

Liu F, Poursine-Laurent J, Link DC. Liu F, et al. Among authors: link dc. Blood. 1997 Oct 1;90(7):2522-8. Blood. 1997. PMID: 9326216 Free article.

7

Interleukin-6 and the granulocyte colony-stimulating factor receptor are major independent regulators of granulopoiesis in vivo but are not required for lineage commitment or terminal differentiation.

Liu F, Poursine-Laurent J, Wu HY, Link DC. Liu F, et al. Among authors: link dc. Blood. 1997 Oct 1;90(7):2583-90. Blood. 1997. PMID: 9326224 Free article.

8

Specific signals generated by the cytoplasmic domain of the granulocyte colony-stimulating factor (G-CSF) receptor are not required for G-CSF-dependent granulocytic differentiation.

Jacob J, Haug JS, Raptis S, Link DC. Jacob J, et al. Among authors: link dc. Blood. 1998 Jul 15;92(2):353-61. Blood. 1998. PMID: 9657731 Free article.

9

Increased granulocyte colony-stimulating factor responsiveness but normal resting granulopoiesis in mice carrying a targeted granulocyte colony-stimulating factor receptor mutation derived from a patient with severe congenital neutropenia.

McLemore ML, Poursine-Laurent J, Link DC. McLemore ML, et al. Among authors: link dc. J Clin Invest. 1998 Aug 1;102(3):483-92. doi: 10.1172/JCI3216. J Clin Invest. 1998. PMID: 9691084 Free PMC article.

10

Expression of the G-CSF receptor on hematopoietic progenitor cells is not required for their mobilization by G-CSF.

Liu F, Poursine-Laurent J, Link DC. Liu F, et al. Among authors: link dc. Blood. 2000 May 15;95(10):3025-31. Blood. 2000. PMID: 10807765 Free article.

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