Michelakis ED - Search Results

1

CD36 expression contributes to age-induced cardiomyopathy in mice.

Koonen DP, Febbraio M, Bonnet S, Nagendran J, Young ME, Michelakis ED, Dyck JR. Koonen DP, et al. Among authors: michelakis ed. Circulation. 2007 Nov 6;116(19):2139-47. doi: 10.1161/CIRCULATIONAHA.107.712901. Epub 2007 Oct 22. Circulation. 2007. PMID: 17967771

2

Dichloroacetate, a metabolic modulator, prevents and reverses chronic hypoxic pulmonary hypertension in rats: role of increased expression and activity of voltage-gated potassium channels.

Michelakis ED, McMurtry MS, Wu XC, Dyck JR, Moudgil R, Hopkins TA, Lopaschuk GD, Puttagunta L, Waite R, Archer SL. Michelakis ED, et al. Circulation. 2002 Jan 15;105(2):244-50. doi: 10.1161/hc0202.101974. Circulation. 2002. PMID: 11790708

3

Gene transfer and metabolic modulators as new therapies for pulmonary hypertension. Increasing expression and activity of potassium channels in rat and human models.

Michelakis ED, Dyck JR, McMurtry MS, Wang S, Wu XC, Moudgil R, Hashimoto K, Puttagunta L, Archer SL. Michelakis ED, et al. Adv Exp Med Biol. 2001;502:401-18. doi: 10.1007/978-1-4757-3401-0_26. Adv Exp Med Biol. 2001. PMID: 11950153

4

Oral sildenafil is an effective and specific pulmonary vasodilator in patients with pulmonary arterial hypertension: comparison with inhaled nitric oxide.

Michelakis E, Tymchak W, Lien D, Webster L, Hashimoto K, Archer S. Michelakis E, et al. Circulation. 2002 May 21;105(20):2398-403. doi: 10.1161/01.cir.0000016641.12984.dc. Circulation. 2002. PMID: 12021227 Clinical Trial.

5

Diversity in mitochondrial function explains differences in vascular oxygen sensing.

Michelakis ED, Hampl V, Nsair A, Wu X, Harry G, Haromy A, Gurtu R, Archer SL. Michelakis ED, et al. Circ Res. 2002 Jun 28;90(12):1307-15. doi: 10.1161/01.res.0000024689.07590.c2. Circ Res. 2002. PMID: 12089069

6

O2 sensing in the human ductus arteriosus: regulation of voltage-gated K+ channels in smooth muscle cells by a mitochondrial redox sensor.

Michelakis ED, Rebeyka I, Wu X, Nsair A, Thébaud B, Hashimoto K, Dyck JR, Haromy A, Harry G, Barr A, Archer SL. Michelakis ED, et al. Circ Res. 2002 Sep 20;91(6):478-86. doi: 10.1161/01.res.0000035057.63303.d1. Circ Res. 2002. PMID: 12242265

7

Endothelium-derived hyperpolarizing factor in human internal mammary artery is 11,12-epoxyeicosatrienoic acid and causes relaxation by activating smooth muscle BK(Ca) channels.

Archer SL, Gragasin FS, Wu X, Wang S, McMurtry S, Kim DH, Platonov M, Koshal A, Hashimoto K, Campbell WB, Falck JR, Michelakis ED. Archer SL, et al. Among authors: michelakis ed. Circulation. 2003 Feb 11;107(5):769-76. doi: 10.1161/01.cir.0000047278.28407.c2. Circulation. 2003. PMID: 12578883

8

In vivo gene transfer of the O2-sensitive potassium channel Kv1.5 reduces pulmonary hypertension and restores hypoxic pulmonary vasoconstriction in chronically hypoxic rats.

Pozeg ZI, Michelakis ED, McMurtry MS, Thébaud B, Wu XC, Dyck JR, Hashimoto K, Wang S, Moudgil R, Harry G, Sultanian R, Koshal A, Archer SL. Pozeg ZI, et al. Among authors: michelakis ed. Circulation. 2003 Apr 22;107(15):2037-44. doi: 10.1161/01.CIR.0000062688.76508.B3. Epub 2003 Apr 14. Circulation. 2003. PMID: 12695303

9

Long-term treatment with oral sildenafil is safe and improves functional capacity and hemodynamics in patients with pulmonary arterial hypertension.

Michelakis ED, Tymchak W, Noga M, Webster L, Wu XC, Lien D, Wang SH, Modry D, Archer SL. Michelakis ED, et al. Circulation. 2003 Oct 28;108(17):2066-9. doi: 10.1161/01.CIR.0000099502.17776.C2. Epub 2003 Oct 20. Circulation. 2003. PMID: 14568893 Clinical Trial.

10

Preferential expression and function of voltage-gated, O2-sensitive K+ channels in resistance pulmonary arteries explains regional heterogeneity in hypoxic pulmonary vasoconstriction: ionic diversity in smooth muscle cells.

Archer SL, Wu XC, Thébaud B, Nsair A, Bonnet S, Tyrrell B, McMurtry MS, Hashimoto K, Harry G, Michelakis ED. Archer SL, et al. Among authors: michelakis ed. Circ Res. 2004 Aug 6;95(3):308-18. doi: 10.1161/01.RES.0000137173.42723.fb. Epub 2004 Jun 24. Circ Res. 2004. PMID: 15217912

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