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Variants of the elongator protein 3 (ELP3) gene are associated with motor neuron degeneration.
Simpson CL, Lemmens R, Miskiewicz K, Broom WJ, Hansen VK, van Vught PW, Landers JE, Sapp P, Van Den Bosch L, Knight J, Neale BM, Turner MR, Veldink JH, Ophoff RA, Tripathi VB, Beleza A, Shah MN, Proitsi P, Van Hoecke A, Carmeliet P, Horvitz HR, Leigh PN, Shaw CE, van den Berg LH, Sham PC, Powell JF, Verstreken P, Brown RH Jr, Robberecht W, Al-Chalabi A. Simpson CL, et al. Among authors: van den berg lh, van vught pw, van den bosch l, van hoecke a. Hum Mol Genet. 2009 Feb 1;18(3):472-81. doi: 10.1093/hmg/ddn375. Epub 2008 Nov 7. Hum Mol Genet. 2009. PMID: 18996918 Free PMC article.
Amyotrophic lateral sclerosis: pathogenesis.
Robberecht W, Van Den Bosch L, Vleminckx V. Robberecht W, et al. Among authors: van den bosch l. Acta Neurol Belg. 2000 Sep;100(3):181-7. Acta Neurol Belg. 2000. PMID: 11098292 Review. No abstract available.
Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration.
Oosthuyse B, Moons L, Storkebaum E, Beck H, Nuyens D, Brusselmans K, Van Dorpe J, Hellings P, Gorselink M, Heymans S, Theilmeier G, Dewerchin M, Laudenbach V, Vermylen P, Raat H, Acker T, Vleminckx V, Van Den Bosch L, Cashman N, Fujisawa H, Drost MR, Sciot R, Bruyninckx F, Hicklin DJ, Ince C, Gressens P, Lupu F, Plate KH, Robberecht W, Herbert JM, Collen D, Carmeliet P. Oosthuyse B, et al. Among authors: van dorpe j, van den bosch l. Nat Genet. 2001 Jun;28(2):131-8. doi: 10.1038/88842. Nat Genet. 2001. PMID: 11381259
Protective effect of parvalbumin on excitotoxic motor neuron death.
Van Den Bosch L, Schwaller B, Vleminckx V, Meijers B, Stork S, Ruehlicke T, Van Houtte E, Klaassen H, Celio MR, Missiaen L, Robberecht W, Berchtold MW. Van Den Bosch L, et al. Among authors: van houtte e. Exp Neurol. 2002 Apr;174(2):150-61. doi: 10.1006/exnr.2001.7858. Exp Neurol. 2002. PMID: 11922657
342 results