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AMPK-independent pathways regulate skeletal muscle fatty acid oxidation.
Dzamko N, Schertzer JD, Ryall JG, Steel R, Macaulay SL, Wee S, Chen ZP, Michell BJ, Oakhill JS, Watt MJ, Jørgensen SB, Lynch GS, Kemp BE, Steinberg GR. Dzamko N, et al. Among authors: jorgensen sb. J Physiol. 2008 Dec 1;586(23):5819-31. doi: 10.1113/jphysiol.2008.159814. Epub 2008 Oct 9. J Physiol. 2008. PMID: 18845612 Free PMC article.
Whole body deletion of AMP-activated protein kinase {beta}2 reduces muscle AMPK activity and exercise capacity.
Steinberg GR, O'Neill HM, Dzamko NL, Galic S, Naim T, Koopman R, Jørgensen SB, Honeyman J, Hewitt K, Chen ZP, Schertzer JD, Scott JW, Koentgen F, Lynch GS, Watt MJ, van Denderen BJ, Campbell DJ, Kemp BE. Steinberg GR, et al. Among authors: jorgensen sb. J Biol Chem. 2010 Nov 26;285(48):37198-209. doi: 10.1074/jbc.M110.102434. Epub 2010 Sep 20. J Biol Chem. 2010. PMID: 20855892 Free PMC article.
AMP-activated protein kinase (AMPK) beta1beta2 muscle null mice reveal an essential role for AMPK in maintaining mitochondrial content and glucose uptake during exercise.
O'Neill HM, Maarbjerg SJ, Crane JD, Jeppesen J, Jørgensen SB, Schertzer JD, Shyroka O, Kiens B, van Denderen BJ, Tarnopolsky MA, Kemp BE, Richter EA, Steinberg GR. O'Neill HM, et al. Among authors: jorgensen sb. Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):16092-7. doi: 10.1073/pnas.1105062108. Epub 2011 Sep 6. Proc Natl Acad Sci U S A. 2011. PMID: 21896769 Free PMC article.
Deletion of skeletal muscle SOCS3 prevents insulin resistance in obesity.
Jorgensen SB, O'Neill HM, Sylow L, Honeyman J, Hewitt KA, Palanivel R, Fullerton MD, Öberg L, Balendran A, Galic S, van der Poel C, Trounce IA, Lynch GS, Schertzer JD, Steinberg GR. Jorgensen SB, et al. Diabetes. 2013 Jan;62(1):56-64. doi: 10.2337/db12-0443. Epub 2012 Sep 6. Diabetes. 2013. PMID: 22961088 Free PMC article.
107 results