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The hyper-IgE syndrome is not caused by a microdeletion syndrome.
Pfeifer D, Woellner C, Petersen A, Pietrogrande MC, Franco JL, Yeganeh M, Ehl S, Matamoros N, Sprecher E, Puck JM, Veelken H, Grimbacher B. Pfeifer D, et al. Immunogenetics. 2007 Dec;59(12):913-26. doi: 10.1007/s00251-007-0257-z. Epub 2007 Nov 14. Immunogenetics. 2007. PMID: 18000661
PIM kinases are essential for chronic lymphocytic leukemia cell survival (PIM2/3) and CXCR4-mediated microenvironmental interactions (PIM1).
Decker S, Finter J, Forde AJ, Kissel S, Schwaller J, Mack TS, Kuhn A, Gray N, Follo M, Jumaa H, Burger M, Zirlik K, Pfeifer D, Miduturu CV, Eibel H, Veelken H, Dierks C. Decker S, et al. Among authors: pfeifer d. Mol Cancer Ther. 2014 May;13(5):1231-45. doi: 10.1158/1535-7163.MCT-13-0575-T. Epub 2014 Mar 21. Mol Cancer Ther. 2014. PMID: 24659821
286 results