Balmanno K - Search Results

1

Phase II trial of trimelamol in refractory ovarian cancer.

Judson IR, Calvert AH, Gore ME, Balmanno K, Gumbrell LA, Perren T, Wiltshaw E. Judson IR, et al. Among authors: balmanno k. Br J Cancer. 1991 Feb;63(2):311-3. doi: 10.1038/bjc.1991.72. Br J Cancer. 1991. PMID: 1997112 Free PMC article. Clinical Trial.

2

The relationship between intrinsic thymidylate synthase expression and sensitivity to THYMITAQ in human leukaemia and colorectal carcinoma cell lines.

Estlin EJ, Balmanno K, Calvert AH, Hall AG, Lunec J, Newell DR, Pearson AD, Taylor GA. Estlin EJ, et al. Among authors: balmanno k. Br J Cancer. 1997;76(12):1579-85. doi: 10.1038/bjc.1997.600. Br J Cancer. 1997. PMID: 9413945 Free PMC article.

3

Pharmacokinetics and pharmacodynamics of prolonged oral etoposide in women with metastatic breast cancer.

Millward MJ, Newell DR, Yuen K, Matthews JP, Balmanno K, Charlton CJ, Gumbrell L, Lind MJ, Chapman F, Proctor M, et al. Millward MJ, et al. Among authors: balmanno k. Cancer Chemother Pharmacol. 1995;37(1-2):161-7. doi: 10.1007/BF00685644. Cancer Chemother Pharmacol. 1995. PMID: 7497587 Clinical Trial.

4

Estimation of the in vitro and in vivo inhibitory effects of antifolates upon thymidylate synthase (TS) in whole cells.

Taylor GA, Jackman AL, Balmanno K, Hughes LR, Calvert AH. Taylor GA, et al. Among authors: balmanno k. Adv Exp Med Biol. 1989;253B:383-8. doi: 10.1007/978-1-4684-5676-9_56. Adv Exp Med Biol. 1989. PMID: 2610126 No abstract available.

5

Phase I and pharmacokinetic study of a water-soluble etoposide prodrug, etoposide phosphate (BMY-40481).

Millward MJ, Newell DR, Mummaneni V, Igwemezie LN, Balmanno K, Charlton CJ, Gumbrell L, Lind MJ, Chapman F, Proctor M, et al. Millward MJ, et al. Among authors: balmanno k. Eur J Cancer. 1995 Dec;31A(13-14):2409-11. doi: 10.1016/0959-8049(95)00331-2. Eur J Cancer. 1995. PMID: 8652278 Clinical Trial.

6

Clinical pharmacokinetic and pharmacodynamic studies with the nonclassical antifolate thymidylate synthase inhibitor 3, 4-dihydro-2-amino-6-methyl-4-oxo-5-(4-pyridylthio)-quinazolone dihydrochloride (AG337) given by 24-hour continuous intravenous infusion.

Rafi I, Taylor GA, Calvete JA, Boddy AV, Balmanno K, Bailey N, Lind M, Calvert AH, Webber S, Jackson RC, et al. Rafi I, et al. Among authors: balmanno k. Clin Cancer Res. 1995 Nov;1(11):1275-84. Clin Cancer Res. 1995. PMID: 9815922 Clinical Trial.

7

Carboplatin pharmacokinetics in children: the development of a pediatric dosing formula. The United Kingdom Children's Cancer Study Group.

Newell DR, Pearson AD, Balmanno K, Price L, Wyllie RA, Keir M, Calvert AH, Lewis IJ, Pinkerton CR, Stevens MC. Newell DR, et al. Among authors: balmanno k. J Clin Oncol. 1993 Dec;11(12):2314-23. doi: 10.1200/JCO.1993.11.12.2314. J Clin Oncol. 1993. PMID: 8246021

8

Intrinsic resistance to the MEK1/2 inhibitor AZD6244 (ARRY-142886) is associated with weak ERK1/2 signalling and/or strong PI3K signalling in colorectal cancer cell lines.

Balmanno K, Chell SD, Gillings AS, Hayat S, Cook SJ. Balmanno K, et al. Int J Cancer. 2009 Nov 15;125(10):2332-41. doi: 10.1002/ijc.24604. Int J Cancer. 2009. PMID: 19637312

9

Apoptosis and autophagy: BIM as a mediator of tumour cell death in response to oncogene-targeted therapeutics.

Gillings AS, Balmanno K, Wiggins CM, Johnson M, Cook SJ. Gillings AS, et al. Among authors: balmanno k. FEBS J. 2009 Nov;276(21):6050-62. doi: 10.1111/j.1742-4658.2009.07329.x. Epub 2009 Sep 29. FEBS J. 2009. PMID: 19788418 Free article. Review.

10

Amplification of the driving oncogene, KRAS or BRAF, underpins acquired resistance to MEK1/2 inhibitors in colorectal cancer cells.

Little AS, Balmanno K, Sale MJ, Newman S, Dry JR, Hampson M, Edwards PA, Smith PD, Cook SJ. Little AS, et al. Among authors: balmanno k. Sci Signal. 2011 Mar 29;4(166):ra17. doi: 10.1126/scisignal.2001752. Sci Signal. 2011. Corrected and republished in: Sci Signal. 2011;4(170):er2. doi: 10.1126/scisignal.4170er2. PMID: 21447798 Corrected and republished.

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