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Phenylacetic acid regioisomers possessing a N-difluoromethyl-1,2-dihydropyrid-2-one pharmacophore: evaluation as dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity.
Yu G, Chowdhury MA, Abdellatif KR, Dong Y, Praveen Rao PN, Das D, Velázquez CA, Suresh MR, Knaus EE. Yu G, et al. Among authors: velazquez ca. Bioorg Med Chem Lett. 2010 Feb 1;20(3):896-902. doi: 10.1016/j.bmcl.2009.12.073. Epub 2009 Dec 23. Bioorg Med Chem Lett. 2010. PMID: 20045320
Synthesis and biological evaluation of salicylic acid and N-acetyl-2-carboxybenzenesulfonamide regioisomers possessing a N-difluoromethyl-1,2-dihydropyrid-2-one pharmacophore: dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity.
Chowdhury MA, Abdellatif KR, Dong Y, Das D, Yu G, Velázquez CA, Suresh MR, Knaus EE. Chowdhury MA, et al. Among authors: velazquez ca. Bioorg Med Chem Lett. 2009 Dec 15;19(24):6855-61. doi: 10.1016/j.bmcl.2009.10.083. Epub 2009 Oct 23. Bioorg Med Chem Lett. 2009. PMID: 19884005
Celecoxib analogs possessing a N-(4-nitrooxybutyl)piperidin-4-yl or N-(4-nitrooxybutyl)-1,2,3,6-tetrahydropyridin-4-yl nitric oxide donor moiety: synthesis, biological evaluation and nitric oxide release studies.
Chowdhury MA, Abdellatif KR, Dong Y, Yu G, Huang Z, Rahman M, Das D, Velázquez CA, Suresh MR, Knaus EE. Chowdhury MA, et al. Among authors: velazquez ca. Bioorg Med Chem Lett. 2010 Feb 15;20(4):1324-9. doi: 10.1016/j.bmcl.2010.01.014. Epub 2010 Jan 11. Bioorg Med Chem Lett. 2010. PMID: 20097072
84 results