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Page 1
Celecoxib analogs possessing a N-(4-nitrooxybutyl)piperidin-4-yl or N-(4-nitrooxybutyl)-1,2,3,6-tetrahydropyridin-4-yl nitric oxide donor moiety: synthesis, biological evaluation and nitric oxide release studies.
Chowdhury MA, Abdellatif KR, Dong Y, Yu G, Huang Z, Rahman M, Das D, Velázquez CA, Suresh MR, Knaus EE. Chowdhury MA, et al. Among authors: suresh mr. Bioorg Med Chem Lett. 2010 Feb 15;20(4):1324-9. doi: 10.1016/j.bmcl.2010.01.014. Epub 2010 Jan 11. Bioorg Med Chem Lett. 2010. PMID: 20097072
Diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of 5-(4-hydroxymethylphenyl)-1-(4-aminosulfonylphenyl)-3-trifluoromethyl-1H-pyrazole and its methanesulfonyl analog: synthesis, biological evaluation and nitric oxide release studies.
Abdellatif KR, Chowdhury MA, Dong Y, Velázquez C, Das D, Suresh MR, Knaus EE. Abdellatif KR, et al. Among authors: suresh mr. Bioorg Med Chem. 2008 Nov 15;16(22):9694-8. doi: 10.1016/j.bmc.2008.10.001. Epub 2008 Oct 5. Bioorg Med Chem. 2008. PMID: 18930406
Synthesis of 1-(methanesulfonyl- and aminosulfonylphenyl)acetylenes that possess a 2-(N-difluoromethyl-1,2-dihydropyridin-2-one) pharmacophore: evaluation as dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity.
Chowdhury MA, Abdellatif KR, Dong Y, Rahman M, Das D, Suresh MR, Knaus EE. Chowdhury MA, et al. Among authors: suresh mr. Bioorg Med Chem Lett. 2009 Feb 1;19(3):584-8. doi: 10.1016/j.bmcl.2008.12.066. Epub 2008 Dec 24. Bioorg Med Chem Lett. 2009. PMID: 19136259
Diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of 5-(4-carboxymethylphenyl)-1-(4-methanesulfonylphenyl)-3-trifluoromethyl-1H-pyrazole and its aminosulfonyl analog: Synthesis, biological evaluation and nitric oxide release studies.
Abdellatif KR, Chowdhury MA, Dong Y, Das D, Yu G, Velázquez C, Suresh MR, Knaus EE. Abdellatif KR, et al. Among authors: suresh mr. Bioorg Med Chem. 2009 Jul 15;17(14):5182-8. doi: 10.1016/j.bmc.2009.05.046. Epub 2009 May 27. Bioorg Med Chem. 2009. PMID: 19500994
Synthesis and biological evaluation of salicylic acid and N-acetyl-2-carboxybenzenesulfonamide regioisomers possessing a N-difluoromethyl-1,2-dihydropyrid-2-one pharmacophore: dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity.
Chowdhury MA, Abdellatif KR, Dong Y, Das D, Yu G, Velázquez CA, Suresh MR, Knaus EE. Chowdhury MA, et al. Among authors: suresh mr. Bioorg Med Chem Lett. 2009 Dec 15;19(24):6855-61. doi: 10.1016/j.bmcl.2009.10.083. Epub 2009 Oct 23. Bioorg Med Chem Lett. 2009. PMID: 19884005
Phenylacetic acid regioisomers possessing a N-difluoromethyl-1,2-dihydropyrid-2-one pharmacophore: evaluation as dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity.
Yu G, Chowdhury MA, Abdellatif KR, Dong Y, Praveen Rao PN, Das D, Velázquez CA, Suresh MR, Knaus EE. Yu G, et al. Among authors: suresh mr. Bioorg Med Chem Lett. 2010 Feb 1;20(3):896-902. doi: 10.1016/j.bmcl.2009.12.073. Epub 2009 Dec 23. Bioorg Med Chem Lett. 2010. PMID: 20045320
154 results