Lankheet NA - Search Results

1

Phase 1 study of combination treatment with PTK 787/ZK 222584 and cetuximab for patients with advanced solid tumors: safety, pharmacokinetics, pharmacodynamics analysis.

Langenberg MH, Witteveen PO, Lankheet NA, Roodhart JM, Rosing H, van den Heuvel IJ, Beijnen JH, Voest EE. Langenberg MH, et al. Among authors: lankheet na. Neoplasia. 2010 Feb;12(2):206-13. doi: 10.1593/neo.91864. Neoplasia. 2010. PMID: 20126478 Free PMC article. Clinical Trial.

2

Brain accumulation of dasatinib is restricted by P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) and can be enhanced by elacridar treatment.

Lagas JS, van Waterschoot RA, van Tilburg VA, Hillebrand MJ, Lankheet N, Rosing H, Beijnen JH, Schinkel AH. Lagas JS, et al. Clin Cancer Res. 2009 Apr 1;15(7):2344-51. doi: 10.1158/1078-0432.CCR-08-2253. Epub 2009 Mar 10. Clin Cancer Res. 2009. PMID: 19276246

3

Erlotinib and pantoprazole: a relevant interaction or not?

Ter Heine R, Fanggiday JC, Lankheet NA, Beijnen JH, Van Der Westerlaken MM, Staaks GH, Malingré MM. Ter Heine R, et al. Among authors: lankheet na. Br J Clin Pharmacol. 2010 Dec;70(6):908-11. doi: 10.1111/j.1365-2125.2010.03748.x. Br J Clin Pharmacol. 2010. PMID: 21175447 Free PMC article.

4

Brain accumulation of sunitinib is restricted by P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) and can be enhanced by oral elacridar and sunitinib coadministration.

Tang SC, Lagas JS, Lankheet NA, Poller B, Hillebrand MJ, Rosing H, Beijnen JH, Schinkel AH. Tang SC, et al. Among authors: lankheet na. Int J Cancer. 2012 Jan 1;130(1):223-33. doi: 10.1002/ijc.26000. Epub 2011 Apr 7. Int J Cancer. 2012. PMID: 21351087

5

Determination of sunitinib and its active metabolite N-desethylsunitinib in sweat of a patient.

Lankheet NA, Blank CU, Mallo H, Adriaansz S, Rosing H, Schellens JH, Huitema AD, Beijnen JH. Lankheet NA, et al. J Anal Toxicol. 2011 Oct;35(8):558-65. doi: 10.1093/anatox/35.8.558. J Anal Toxicol. 2011. PMID: 22004675

6

Fatal interstitial lung disease associated with high erlotinib and metabolite levels. A case report and a review of the literature.

ter Heine R, van den Bosch RT, Schaefer-Prokop CM, Lankheet NA, Beijnen JH, Staaks GH, van der Westerlaken MM, Malingré MM, van den Brand JJ. ter Heine R, et al. Among authors: lankheet na. Lung Cancer. 2012 Mar;75(3):391-7. doi: 10.1016/j.lungcan.2011.10.008. Epub 2011 Nov 17. Lung Cancer. 2012. PMID: 22101147 Review.

7

P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) restrict brain accumulation of the active sunitinib metabolite N-desethyl sunitinib.

Tang SC, Lankheet NA, Poller B, Wagenaar E, Beijnen JH, Schinkel AH. Tang SC, et al. Among authors: lankheet na. J Pharmacol Exp Ther. 2012 Apr;341(1):164-73. doi: 10.1124/jpet.111.186908. Epub 2012 Jan 11. J Pharmacol Exp Ther. 2012. PMID: 22238213

8

Method development and validation for the quantification of dasatinib, erlotinib, gefitinib, imatinib, lapatinib, nilotinib, sorafenib and sunitinib in human plasma by liquid chromatography coupled with tandem mass spectrometry.

Lankheet NA, Hillebrand MJ, Rosing H, Schellens JH, Beijnen JH, Huitema AD. Lankheet NA, et al. Biomed Chromatogr. 2013 Apr;27(4):466-76. doi: 10.1002/bmc.2814. Epub 2012 Sep 17. Biomed Chromatogr. 2013. PMID: 22987603

9

Quantitative determination of erlotinib and O-desmethyl erlotinib in human EDTA plasma and lung tumor tissue.

Lankheet NA, Schaake EE, Rosing H, Burgers JA, Schellens JH, Beijnen JH, Huitema AD. Lankheet NA, et al. Bioanalysis. 2012 Nov;4(21):2563-77. doi: 10.4155/bio.12.235. Bioanalysis. 2012. PMID: 23173792

10

Quantification of sunitinib and N-desethyl sunitinib in human EDTA plasma by liquid chromatography coupled with electrospray ionization tandem mass spectrometry: validation and application in routine therapeutic drug monitoring.

Lankheet NA, Steeghs N, Rosing H, Schellens JH, Beijnen JH, Huitema AD. Lankheet NA, et al. Ther Drug Monit. 2013 Apr;35(2):168-76. doi: 10.1097/FTD.0b013e31827efd9e. Ther Drug Monit. 2013. PMID: 23503442 Clinical Trial.

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