Tennant DA - Search Results

1

IDH1 mutations in gliomas: when an enzyme loses its grip.

Frezza C, Tennant DA, Gottlieb E. Frezza C, et al. Among authors: tennant da. Cancer Cell. 2010 Jan 19;17(1):7-9. doi: 10.1016/j.ccr.2009.12.031. Cancer Cell. 2010. PMID: 20129244 Free article.

2

Cell-permeating alpha-ketoglutarate derivatives alleviate pseudohypoxia in succinate dehydrogenase-deficient cells.

MacKenzie ED, Selak MA, Tennant DA, Payne LJ, Crosby S, Frederiksen CM, Watson DG, Gottlieb E. MacKenzie ED, et al. Among authors: tennant da. Mol Cell Biol. 2007 May;27(9):3282-9. doi: 10.1128/MCB.01927-06. Epub 2007 Feb 26. Mol Cell Biol. 2007. PMID: 17325041 Free PMC article.

3

Metabolic transformation in cancer.

Tennant DA, Durán RV, Boulahbel H, Gottlieb E. Tennant DA, et al. Carcinogenesis. 2009 Aug;30(8):1269-80. doi: 10.1093/carcin/bgp070. Epub 2009 Mar 25. Carcinogenesis. 2009. PMID: 19321800 Review.

4

Reactivating HIF prolyl hydroxylases under hypoxia results in metabolic catastrophe and cell death.

Tennant DA, Frezza C, MacKenzie ED, Nguyen QD, Zheng L, Selak MA, Roberts DL, Dive C, Watson DG, Aboagye EO, Gottlieb E. Tennant DA, et al. Oncogene. 2009 Nov 12;28(45):4009-21. doi: 10.1038/onc.2009.250. Epub 2009 Aug 31. Oncogene. 2009. PMID: 19718054

5

Targeting metabolic transformation for cancer therapy.

Tennant DA, Durán RV, Gottlieb E. Tennant DA, et al. Nat Rev Cancer. 2010 Apr;10(4):267-77. doi: 10.1038/nrc2817. Epub 2010 Mar 19. Nat Rev Cancer. 2010. PMID: 20300106 Review.

6

HIF prolyl hydroxylase-3 mediates alpha-ketoglutarate-induced apoptosis and tumor suppression.

Tennant DA, Gottlieb E. Tennant DA, et al. J Mol Med (Berl). 2010 Aug;88(8):839-49. doi: 10.1007/s00109-010-0627-0. Epub 2010 Apr 11. J Mol Med (Berl). 2010. PMID: 20383689

7

Metabolic profiling of hypoxic cells revealed a catabolic signature required for cell survival.

Frezza C, Zheng L, Tennant DA, Papkovsky DB, Hedley BA, Kalna G, Watson DG, Gottlieb E. Frezza C, et al. Among authors: tennant da. PLoS One. 2011;6(9):e24411. doi: 10.1371/journal.pone.0024411. Epub 2011 Sep 2. PLoS One. 2011. PMID: 21912692 Free PMC article.

8

A roadmap for interpreting (13)C metabolite labeling patterns from cells.

Buescher JM, Antoniewicz MR, Boros LG, Burgess SC, Brunengraber H, Clish CB, DeBerardinis RJ, Feron O, Frezza C, Ghesquiere B, Gottlieb E, Hiller K, Jones RG, Kamphorst JJ, Kibbey RG, Kimmelman AC, Locasale JW, Lunt SY, Maddocks OD, Malloy C, Metallo CM, Meuillet EJ, Munger J, Nöh K, Rabinowitz JD, Ralser M, Sauer U, Stephanopoulos G, St-Pierre J, Tennant DA, Wittmann C, Vander Heiden MG, Vazquez A, Vousden K, Young JD, Zamboni N, Fendt SM. Buescher JM, et al. Among authors: tennant da. Curr Opin Biotechnol. 2015 Aug;34:189-201. doi: 10.1016/j.copbio.2015.02.003. Epub 2015 Feb 28. Curr Opin Biotechnol. 2015. PMID: 25731751 Free PMC article. Review.

9

Oncogenic IDH1 Mutations Promote Enhanced Proline Synthesis through PYCR1 to Support the Maintenance of Mitochondrial Redox Homeostasis.

Hollinshead KER, Munford H, Eales KL, Bardella C, Li C, Escribano-Gonzalez C, Thakker A, Nonnenmacher Y, Kluckova K, Jeeves M, Murren R, Cuozzo F, Ye D, Laurenti G, Zhu W, Hiller K, Hodson DJ, Hua W, Tomlinson IP, Ludwig C, Mao Y, Tennant DA. Hollinshead KER, et al. Among authors: tennant da. Cell Rep. 2018 Mar 20;22(12):3107-3114. doi: 10.1016/j.celrep.2018.02.084. Cell Rep. 2018. PMID: 29562167 Free PMC article.

10

PK-M2 Makes Cells Sweeter on HIF1.

Tennant DA. Tennant DA. Cell. 2011 May 27;145(5):647-9. doi: 10.1016/j.cell.2011.05.009. Cell. 2011. PMID: 21620132 Free article.

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