Stevens RC - Search Results

1

Ligand binding and subtype selectivity of the human A(2A) adenosine receptor: identification and characterization of essential amino acid residues.

Jaakola VP, Lane JR, Lin JY, Katritch V, Ijzerman AP, Stevens RC. Jaakola VP, et al. Among authors: stevens rc. J Biol Chem. 2010 Apr 23;285(17):13032-44. doi: 10.1074/jbc.M109.096974. Epub 2010 Feb 10. J Biol Chem. 2010. PMID: 20147292 Free PMC article.

2

The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist.

Jaakola VP, Griffith MT, Hanson MA, Cherezov V, Chien EY, Lane JR, Ijzerman AP, Stevens RC. Jaakola VP, et al. Among authors: stevens rc. Science. 2008 Nov 21;322(5905):1211-7. doi: 10.1126/science.1164772. Epub 2008 Oct 2. Science. 2008. PMID: 18832607 Free PMC article.

3

Structure-based discovery of novel chemotypes for adenosine A(2A) receptor antagonists.

Katritch V, Jaakola VP, Lane JR, Lin J, Ijzerman AP, Yeager M, Kufareva I, Stevens RC, Abagyan R. Katritch V, et al. Among authors: stevens rc. J Med Chem. 2010 Feb 25;53(4):1799-809. doi: 10.1021/jm901647p. J Med Chem. 2010. PMID: 20095623 Free PMC article.

4

Structure of an agonist-bound human A2A adenosine receptor.

Xu F, Wu H, Katritch V, Han GW, Jacobson KA, Gao ZG, Cherezov V, Stevens RC. Xu F, et al. Among authors: stevens rc. Science. 2011 Apr 15;332(6027):322-7. doi: 10.1126/science.1202793. Epub 2011 Mar 10. Science. 2011. PMID: 21393508 Free PMC article.

5

The role of a sodium ion binding site in the allosteric modulation of the A(2A) adenosine G protein-coupled receptor.

Gutiérrez-de-Terán H, Massink A, Rodríguez D, Liu W, Han GW, Joseph JS, Katritch I, Heitman LH, Xia L, Ijzerman AP, Cherezov V, Katritch V, Stevens RC. Gutiérrez-de-Terán H, et al. Among authors: stevens rc. Structure. 2013 Dec 3;21(12):2175-85. doi: 10.1016/j.str.2013.09.020. Epub 2013 Nov 7. Structure. 2013. PMID: 24210756 Free PMC article.

6

Sodium ion binding pocket mutations and adenosine A2A receptor function.

Massink A, Gutiérrez-de-Terán H, Lenselink EB, Ortiz Zacarías NV, Xia L, Heitman LH, Katritch V, Stevens RC, IJzerman AP. Massink A, et al. Among authors: stevens rc. Mol Pharmacol. 2015 Feb;87(2):305-13. doi: 10.1124/mol.114.095737. Epub 2014 Dec 3. Mol Pharmacol. 2015. PMID: 25473121 Free PMC article.

7

Structural Basis for Ligand Recognition and Functional Selectivity at Angiotensin Receptor.

Zhang H, Unal H, Desnoyer R, Han GW, Patel N, Katritch V, Karnik SS, Cherezov V, Stevens RC. Zhang H, et al. Among authors: stevens rc. J Biol Chem. 2015 Dec 4;290(49):29127-39. doi: 10.1074/jbc.M115.689000. Epub 2015 Sep 29. J Biol Chem. 2015. PMID: 26420482 Free PMC article.

8

A specific cholesterol binding site is established by the 2.8 A structure of the human beta2-adrenergic receptor.

Hanson MA, Cherezov V, Griffith MT, Roth CB, Jaakola VP, Chien EY, Velasquez J, Kuhn P, Stevens RC. Hanson MA, et al. Among authors: stevens rc. Structure. 2008 Jun;16(6):897-905. doi: 10.1016/j.str.2008.05.001. Structure. 2008. PMID: 18547522 Free PMC article.

9

Conserved binding mode of human beta2 adrenergic receptor inverse agonists and antagonist revealed by X-ray crystallography.

Wacker D, Fenalti G, Brown MA, Katritch V, Abagyan R, Cherezov V, Stevens RC. Wacker D, et al. Among authors: stevens rc. J Am Chem Soc. 2010 Aug 25;132(33):11443-5. doi: 10.1021/ja105108q. J Am Chem Soc. 2010. PMID: 20669948 Free PMC article.

10

Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist.

Chien EY, Liu W, Zhao Q, Katritch V, Han GW, Hanson MA, Shi L, Newman AH, Javitch JA, Cherezov V, Stevens RC. Chien EY, et al. Among authors: stevens rc. Science. 2010 Nov 19;330(6007):1091-5. doi: 10.1126/science.1197410. Science. 2010. PMID: 21097933 Free PMC article.

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