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TNF and bone.
David JP, Schett G. David JP, et al. Among authors: schett g. Curr Dir Autoimmun. 2010;11:135-44. doi: 10.1159/000289202. Epub 2010 Feb 18. Curr Dir Autoimmun. 2010. PMID: 20173392 Review.
Osteoclasts are essential for TNF-alpha-mediated joint destruction.
Redlich K, Hayer S, Ricci R, David JP, Tohidast-Akrad M, Kollias G, Steiner G, Smolen JS, Wagner EF, Schett G. Redlich K, et al. Among authors: schett g. J Clin Invest. 2002 Nov;110(10):1419-27. doi: 10.1172/JCI15582. J Clin Invest. 2002. PMID: 12438440 Free PMC article.
Repair of local bone erosions and reversal of systemic bone loss upon therapy with anti-tumor necrosis factor in combination with osteoprotegerin or parathyroid hormone in tumor necrosis factor-mediated arthritis.
Redlich K, Görtz B, Hayer S, Zwerina J, Doerr N, Kostenuik P, Bergmeister H, Kollias G, Steiner G, Smolen JS, Schett G. Redlich K, et al. Among authors: schett g. Am J Pathol. 2004 Feb;164(2):543-55. doi: 10.1016/S0002-9440(10)63144-6. Am J Pathol. 2004. PMID: 14742260 Free PMC article.
JNK1 is not essential for TNF-mediated joint disease.
Köller M, Hayer S, Redlich K, Ricci R, David JP, Steiner G, Smolen JS, Wagner EF, Schett G. Köller M, et al. Among authors: schett g. Arthritis Res Ther. 2005;7(1):R166-73. doi: 10.1186/ar1473. Epub 2004 Dec 7. Arthritis Res Ther. 2005. PMID: 15642137 Free PMC article.
CD44 is a determinant of inflammatory bone loss.
Hayer S, Steiner G, Görtz B, Reiter E, Tohidast-Akrad M, Amling M, Hoffmann O, Redlich K, Zwerina J, Skriner K, Hilberg F, Wagner EF, Smolen JS, Schett G. Hayer S, et al. Among authors: schett g. J Exp Med. 2005 Mar 21;201(6):903-14. doi: 10.1084/jem.20040852. J Exp Med. 2005. PMID: 15781582 Free PMC article.
TNF-induced structural joint damage is mediated by IL-1.
Zwerina J, Redlich K, Polzer K, Joosten L, Krönke G, Distler J, Hess A, Pundt N, Pap T, Hoffmann O, Gasser J, Scheinecker C, Smolen JS, van den Berg W, Schett G. Zwerina J, et al. Among authors: schett g. Proc Natl Acad Sci U S A. 2007 Jul 10;104(28):11742-7. doi: 10.1073/pnas.0610812104. Epub 2007 Jul 3. Proc Natl Acad Sci U S A. 2007. PMID: 17609389 Free PMC article.
1,119 results