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Dopamine D2 receptor dysfunction is rescued by adenosine A2A receptor antagonism in a model of DYT1 dystonia.
Napolitano F, Pasqualetti M, Usiello A, Santini E, Pacini G, Sciamanna G, Errico F, Tassone A, Di Dato V, Martella G, Cuomo D, Fisone G, Bernardi G, Mandolesi G, Mercuri NB, Standaert DG, Pisani A. Napolitano F, et al. Among authors: pasqualetti m. Neurobiol Dis. 2010 Jun;38(3):434-45. doi: 10.1016/j.nbd.2010.03.003. Epub 2010 Mar 19. Neurobiol Dis. 2010. PMID: 20227500 Free PMC article.
The GTP-binding protein Rhes modulates dopamine signalling in striatal medium spiny neurons.
Errico F, Santini E, Migliarini S, Borgkvist A, Centonze D, Nasti V, Carta M, De Chiara V, Prosperetti C, Spano D, Herve D, Pasqualetti M, Di Lauro R, Fisone G, Usiello A. Errico F, et al. Among authors: pasqualetti m. Mol Cell Neurosci. 2008 Feb;37(2):335-45. doi: 10.1016/j.mcn.2007.10.007. Epub 2007 Oct 23. Mol Cell Neurosci. 2008. PMID: 18035555
Rasd2 Modulates Prefronto-Striatal Phenotypes in Humans and 'Schizophrenia-Like Behaviors' in Mice.
Vitucci D, Di Giorgio A, Napolitano F, Pelosi B, Blasi G, Errico F, Attrotto MT, Gelao B, Fazio L, Taurisano P, Di Maio A, Marsili V, Pasqualetti M, Bertolino A, Usiello A. Vitucci D, et al. Among authors: pasqualetti m. Neuropsychopharmacology. 2016 Feb;41(3):916-27. doi: 10.1038/npp.2015.228. Epub 2015 Jul 31. Neuropsychopharmacology. 2016. PMID: 26228524 Free PMC article.
The striatal-enriched protein Rhes is a critical modulator of cocaine-induced molecular and behavioral responses.
Napolitano F, De Rosa A, Russo R, Di Maio A, Garofalo M, Federici M, Migliarini S, Ledonne A, Rizzo FR, Avallone L, Nuzzo T, Biagini T, Pasqualetti M, Mercuri NB, Mazza T, Chambery A, Usiello A. Napolitano F, et al. Among authors: pasqualetti m. Sci Rep. 2019 Oct 25;9(1):15294. doi: 10.1038/s41598-019-51839-w. Sci Rep. 2019. PMID: 31653935 Free PMC article.
RGS9-2 rescues dopamine D2 receptor levels and signaling in DYT1 dystonia mouse models.
Bonsi P, Ponterio G, Vanni V, Tassone A, Sciamanna G, Migliarini S, Martella G, Meringolo M, Dehay B, Doudnikoff E, Zachariou V, Goodchild RE, Mercuri NB, D'Amelio M, Pasqualetti M, Bezard E, Pisani A. Bonsi P, et al. Among authors: pasqualetti m. EMBO Mol Med. 2019 Jan;11(1):e9283. doi: 10.15252/emmm.201809283. EMBO Mol Med. 2019. PMID: 30552094 Free PMC article.
Dysfunctional dopaminergic neurotransmission in asocial BTBR mice.
Squillace M, Dodero L, Federici M, Migliarini S, Errico F, Napolitano F, Krashia P, Di Maio A, Galbusera A, Bifone A, Scattoni ML, Pasqualetti M, Mercuri NB, Usiello A, Gozzi A. Squillace M, et al. Among authors: pasqualetti m. Transl Psychiatry. 2014 Aug 19;4(8):e427. doi: 10.1038/tp.2014.69. Transl Psychiatry. 2014. PMID: 25136890 Free PMC article.
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