Lafyatis R - Search Results

1

Distinct evolution of TLR-mediated dendritic cell cytokine secretion in patients with limited and diffuse cutaneous systemic sclerosis.

van Bon L, Popa C, Huijbens R, Vonk M, York M, Simms R, Hesselstrand R, Wuttge DM, Lafyatis R, Radstake TR. van Bon L, et al. Among authors: lafyatis r. Ann Rheum Dis. 2010 Aug;69(8):1539-47. doi: 10.1136/ard.2009.128207. Epub 2010 May 24. Ann Rheum Dis. 2010. PMID: 20498209

2

Antimalarial agents: closing the gate on Toll-like receptors?

Lafyatis R, York M, Marshak-Rothstein A. Lafyatis R, et al. Arthritis Rheum. 2006 Oct;54(10):3068-70. doi: 10.1002/art.22157. Arthritis Rheum. 2006. PMID: 17009223 No abstract available.

3

A macrophage marker, Siglec-1, is increased on circulating monocytes in patients with systemic sclerosis and induced by type I interferons and toll-like receptor agonists.

York MR, Nagai T, Mangini AJ, Lemaire R, van Seventer JM, Lafyatis R. York MR, et al. Among authors: lafyatis r. Arthritis Rheum. 2007 Mar;56(3):1010-20. doi: 10.1002/art.22382. Arthritis Rheum. 2007. PMID: 17328080

4

Cartilage oligomeric matrix protein expression in systemic sclerosis reveals heterogeneity of dermal fibroblast responses to transforming growth factor beta.

Farina G, Lemaire R, Pancari P, Bayle J, Widom RL, Lafyatis R. Farina G, et al. Among authors: lafyatis r. Ann Rheum Dis. 2009 Mar;68(3):435-41. doi: 10.1136/ard.2007.086850. Epub 2008 Apr 13. Ann Rheum Dis. 2009. PMID: 18408251

5

The -2518A>G promoter polymorphism in the CCL2 gene is not associated with systemic sclerosis susceptibility or phenotype: results from a multicenter study of European Caucasian patients.

Radstake TR, Vonk MC, Dekkers M, Schijvenaars MM, Treppichio WL, Lafyatis R, Riemekasten G, van den Hoogen F, Coenen MJ. Radstake TR, et al. Among authors: lafyatis r. Hum Immunol. 2009 Feb;70(2):130-3. doi: 10.1016/j.humimm.2008.10.012. Epub 2008 Nov 24. Hum Immunol. 2009. PMID: 19032966

6

B cell depletion with rituximab in patients with diffuse cutaneous systemic sclerosis.

Lafyatis R, Kissin E, York M, Farina G, Viger K, Fritzler MJ, Merkel PA, Simms RW. Lafyatis R, et al. Arthritis Rheum. 2009 Feb;60(2):578-83. doi: 10.1002/art.24249. Arthritis Rheum. 2009. PMID: 19180481 Free PMC article. Clinical Trial.

7

Enhanced interleukin-10 production by dendritic cells upon stimulation with Toll-like receptor 4 agonists in systemic sclerosis that is possibly implicated in CCL18 secretion.

van Lieshout AW, Vonk MC, Bredie SJ, Joosten LB, Netea MG, van Riel PL, Lafyatis R, van den Hoogen FH, Radstake TR. van Lieshout AW, et al. Among authors: lafyatis r. Scand J Rheumatol. 2009;38(4):282-90. doi: 10.1080/03009740802572467. Scand J Rheumatol. 2009. PMID: 19255934

8

The pronounced Th17 profile in systemic sclerosis (SSc) together with intracellular expression of TGFbeta and IFNgamma distinguishes SSc phenotypes.

Radstake TR, van Bon L, Broen J, Hussiani A, Hesselstrand R, Wuttge DM, Deng Y, Simms R, Lubberts E, Lafyatis R. Radstake TR, et al. Among authors: lafyatis r. PLoS One. 2009 Jun 17;4(6):e5903. doi: 10.1371/journal.pone.0005903. PLoS One. 2009. PMID: 19536281 Free PMC article.

9

Increased frequency and compromised function of T regulatory cells in systemic sclerosis (SSc) is related to a diminished CD69 and TGFbeta expression.

Radstake TR, van Bon L, Broen J, Wenink M, Santegoets K, Deng Y, Hussaini A, Simms R, Cruikshank WW, Lafyatis R. Radstake TR, et al. Among authors: lafyatis r. PLoS One. 2009 Jun 22;4(6):e5981. doi: 10.1371/journal.pone.0005981. PLoS One. 2009. PMID: 19543397 Free PMC article.

10

Innate immunity and inflammation in systemic sclerosis.

Lafyatis R, York M. Lafyatis R, et al. Curr Opin Rheumatol. 2009 Nov;21(6):617-22. doi: 10.1097/BOR.0b013e32832fd69e. Curr Opin Rheumatol. 2009. PMID: 19633559 Free PMC article. Review.

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