Isom LL - Search Results

1

Efficacy loss of the anticonvulsant carbamazepine in mice lacking sodium channel beta subunits via paradoxical effects on persistent sodium currents.

Uebachs M, Opitz T, Royeck M, Dickhof G, Horstmann MT, Isom LL, Beck H. Uebachs M, et al. Among authors: isom ll. J Neurosci. 2010 Jun 23;30(25):8489-501. doi: 10.1523/JNEUROSCI.1534-10.2010. J Neurosci. 2010. PMID: 20573896 Free PMC article.

2

Contactin associates with Na+ channels and increases their functional expression.

Kazarinova-Noyes K, Malhotra JD, McEwen DP, Mattei LN, Berglund EO, Ranscht B, Levinson SR, Schachner M, Shrager P, Isom LL, Xiao ZC. Kazarinova-Noyes K, et al. Among authors: isom ll. J Neurosci. 2001 Oct 1;21(19):7517-25. doi: 10.1523/JNEUROSCI.21-19-07517.2001. J Neurosci. 2001. PMID: 11567041 Free PMC article.

3

Functional and biochemical analysis of a sodium channel beta1 subunit mutation responsible for generalized epilepsy with febrile seizures plus type 1.

Meadows LS, Malhotra J, Loukas A, Thyagarajan V, Kazen-Gillespie KA, Koopman MC, Kriegler S, Isom LL, Ragsdale DS. Meadows LS, et al. Among authors: isom ll. J Neurosci. 2002 Dec 15;22(24):10699-709. doi: 10.1523/JNEUROSCI.22-24-10699.2002. J Neurosci. 2002. PMID: 12486163 Free PMC article.

4

Mice lacking sodium channel beta1 subunits display defects in neuronal excitability, sodium channel expression, and nodal architecture.

Chen C, Westenbroek RE, Xu X, Edwards CA, Sorenson DR, Chen Y, McEwen DP, O'Malley HA, Bharucha V, Meadows LS, Knudsen GA, Vilaythong A, Noebels JL, Saunders TL, Scheuer T, Shrager P, Catterall WA, Isom LL. Chen C, et al. Among authors: isom ll. J Neurosci. 2004 Apr 21;24(16):4030-42. doi: 10.1523/JNEUROSCI.4139-03.2004. J Neurosci. 2004. PMID: 15102918 Free PMC article.

5

A novel epilepsy mutation in the sodium channel SCN1A identifies a cytoplasmic domain for beta subunit interaction.

Spampanato J, Kearney JA, de Haan G, McEwen DP, Escayg A, Aradi I, MacDonald BT, Levin SI, Soltesz I, Benna P, Montalenti E, Isom LL, Goldin AL, Meisler MH. Spampanato J, et al. Among authors: isom ll. J Neurosci. 2004 Nov 3;24(44):10022-34. doi: 10.1523/JNEUROSCI.2034-04.2004. J Neurosci. 2004. PMID: 15525788 Free PMC article.

6

Upregulation of the voltage-gated sodium channel beta2 subunit in neuropathic pain models: characterization of expression in injured and non-injured primary sensory neurons.

Pertin M, Ji RR, Berta T, Powell AJ, Karchewski L, Tate SN, Isom LL, Woolf CJ, Gilliard N, Spahn DR, Decosterd I. Pertin M, et al. Among authors: isom ll. J Neurosci. 2005 Nov 23;25(47):10970-80. doi: 10.1523/JNEUROSCI.3066-05.2005. J Neurosci. 2005. PMID: 16306410 Free PMC article.

7

Sodium channel beta2 subunits regulate tetrodotoxin-sensitive sodium channels in small dorsal root ganglion neurons and modulate the response to pain.

Lopez-Santiago LF, Pertin M, Morisod X, Chen C, Hong S, Wiley J, Decosterd I, Isom LL. Lopez-Santiago LF, et al. Among authors: isom ll. J Neurosci. 2006 Jul 26;26(30):7984-94. doi: 10.1523/JNEUROSCI.2211-06.2006. J Neurosci. 2006. PMID: 16870743 Free PMC article.

8

Voltage-gated Na+ channel beta1 subunit-mediated neurite outgrowth requires Fyn kinase and contributes to postnatal CNS development in vivo.

Brackenbury WJ, Davis TH, Chen C, Slat EA, Detrow MJ, Dickendesher TL, Ranscht B, Isom LL. Brackenbury WJ, et al. Among authors: isom ll. J Neurosci. 2008 Mar 19;28(12):3246-56. doi: 10.1523/JNEUROSCI.5446-07.2008. J Neurosci. 2008. PMID: 18354028 Free PMC article.

9

scn1bb, a zebrafish ortholog of SCN1B expressed in excitable and nonexcitable cells, affects motor neuron axon morphology and touch sensitivity.

Fein AJ, Wright MA, Slat EA, Ribera AB, Isom LL. Fein AJ, et al. Among authors: isom ll. J Neurosci. 2008 Nov 19;28(47):12510-22. doi: 10.1523/JNEUROSCI.4329-08.2008. J Neurosci. 2008. PMID: 19020043 Free PMC article.

10

Regulation of persistent Na current by interactions between beta subunits of voltage-gated Na channels.

Aman TK, Grieco-Calub TM, Chen C, Rusconi R, Slat EA, Isom LL, Raman IM. Aman TK, et al. Among authors: isom ll. J Neurosci. 2009 Feb 18;29(7):2027-42. doi: 10.1523/JNEUROSCI.4531-08.2009. J Neurosci. 2009. PMID: 19228957 Free PMC article.

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