Parant JM - Search Results

1

Essential roles of Jab1 in cell survival, spontaneous DNA damage and DNA repair.

Tian L, Peng G, Parant JM, Leventaki V, Drakos E, Zhang Q, Parker-Thornburg J, Shackleford TJ, Dai H, Lin SY, Lozano G, Rassidakis GZ, Claret FX. Tian L, et al. Among authors: parant jm. Oncogene. 2010 Nov 18;29(46):6125-37. doi: 10.1038/onc.2010.345. Epub 2010 Aug 30. Oncogene. 2010. PMID: 20802511 Free PMC article.

2

Disrupting TP53 in mouse models of human cancers.

Parant JM, Lozano G. Parant JM, et al. Hum Mutat. 2003 Mar;21(3):321-6. doi: 10.1002/humu.10186. Hum Mutat. 2003. PMID: 12619119 Review.

3

Mutation at p53 serine 389 does not rescue the embryonic lethality in mdm2 or mdm4 null mice.

Iwakuma T, Parant JM, Fasulo M, Zwart E, Jacks T, de Vries A, Lozano G. Iwakuma T, et al. Among authors: parant jm. Oncogene. 2004 Oct 7;23(46):7644-50. doi: 10.1038/sj.onc.1207793. Oncogene. 2004. PMID: 15361844

4

Tissue-specific differences of p53 inhibition by Mdm2 and Mdm4.

Grier JD, Xiong S, Elizondo-Fraire AC, Parant JM, Lozano G. Grier JD, et al. Among authors: parant jm. Mol Cell Biol. 2006 Jan;26(1):192-8. doi: 10.1128/MCB.26.1.192-198.2006. Mol Cell Biol. 2006. PMID: 16354690 Free PMC article.

5

Switching mechanisms of cell death in mdm2- and mdm4-null mice by deletion of p53 downstream targets.

Chavez-Reyes A, Parant JM, Amelse LL, de Oca Luna RM, Korsmeyer SJ, Lozano G. Chavez-Reyes A, et al. Among authors: parant jm. Cancer Res. 2003 Dec 15;63(24):8664-9. Cancer Res. 2003. PMID: 14695178

6

Xenobiotic stress induces hepatomegaly and liver tumors via the nuclear receptor constitutive androstane receptor.

Huang W, Zhang J, Washington M, Liu J, Parant JM, Lozano G, Moore DD. Huang W, et al. Among authors: parant jm. Mol Endocrinol. 2005 Jun;19(6):1646-53. doi: 10.1210/me.2004-0520. Epub 2005 Apr 14. Mol Endocrinol. 2005. PMID: 15831521

7

Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53.

Parant J, Chavez-Reyes A, Little NA, Yan W, Reinke V, Jochemsen AG, Lozano G. Parant J, et al. Nat Genet. 2001 Sep;29(1):92-5. doi: 10.1038/ng714. Nat Genet. 2001. PMID: 11528400

8

Differential roles of p21(Waf1) and p27(Kip1) in modulating chemosensitivity and their possible application in drug discovery studies.

Schmidt M, Lu Y, Parant JM, Lozano G, Bacher G, Beckers T, Fan Z. Schmidt M, et al. Among authors: parant jm. Mol Pharmacol. 2001 Nov;60(5):900-6. doi: 10.1124/mol.60.5.900. Mol Pharmacol. 2001. PMID: 11641417

9

Mtbp haploinsufficiency in mice increases tumor metastasis.

Iwakuma T, Tochigi Y, Van Pelt CS, Caldwell LC, Terzian T, Parant JM, Chau GP, Koch JG, Eischen CM, Lozano G. Iwakuma T, et al. Among authors: parant jm. Oncogene. 2008 Mar 20;27(13):1813-20. doi: 10.1038/sj.onc.1210827. Epub 2007 Oct 1. Oncogene. 2008. PMID: 17906694

10

EWS-FLI1 induces developmental abnormalities and accelerates sarcoma formation in a transgenic mouse model.

Lin PP, Pandey MK, Jin F, Xiong S, Deavers M, Parant JM, Lozano G. Lin PP, et al. Among authors: parant jm. Cancer Res. 2008 Nov 1;68(21):8968-75. doi: 10.1158/0008-5472.CAN-08-0573. Cancer Res. 2008. PMID: 18974141 Free PMC article.

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