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Blood myeloid dendritic cells from HIV-1-infected individuals display a proapoptotic profile characterized by decreased Bcl-2 levels and by caspase-3+ frequencies that are associated with levels of plasma viremia and T cell activation in an exploratory study.
Dillon SM, Friedlander LJ, Rogers LM, Meditz AL, Folkvord JM, Connick E, McCarter MD, Wilson CC. Dillon SM, et al. Among authors: meditz al. J Virol. 2011 Jan;85(1):397-409. doi: 10.1128/JVI.01118-10. Epub 2010 Oct 20. J Virol. 2011. PMID: 20962079 Free PMC article.
CTL fail to accumulate at sites of HIV-1 replication in lymphoid tissue.
Connick E, Mattila T, Folkvord JM, Schlichtemeier R, Meditz AL, Ray MG, McCarter MD, Mawhinney S, Hage A, White C, Skinner PJ. Connick E, et al. Among authors: meditz al. J Immunol. 2007 Jun 1;178(11):6975-83. doi: 10.4049/jimmunol.178.11.6975. J Immunol. 2007. PMID: 17513747 Free article.
Sex, race, and geographic region influence clinical outcomes following primary HIV-1 infection.
Meditz AL, MaWhinney S, Allshouse A, Feser W, Markowitz M, Little S, Hecht R, Daar ES, Collier AC, Margolick J, Kilby JM, Routy JP, Conway B, Kaldor J, Levy J, Schooley R, Cooper DA, Altfeld M, Richman D, Connick E. Meditz AL, et al. J Infect Dis. 2011 Feb 15;203(4):442-51. doi: 10.1093/infdis/jiq085. Epub 2011 Jan 18. J Infect Dis. 2011. PMID: 21245157 Free PMC article.
Inadequate T follicular cell help impairs B cell immunity during HIV infection.
Cubas RA, Mudd JC, Savoye AL, Perreau M, van Grevenynghe J, Metcalf T, Connick E, Meditz A, Freeman GJ, Abesada-Terk G Jr, Jacobson JM, Brooks AD, Crotty S, Estes JD, Pantaleo G, Lederman MM, Haddad EK. Cubas RA, et al. Among authors: meditz a. Nat Med. 2013 Apr;19(4):494-9. doi: 10.1038/nm.3109. Epub 2013 Mar 10. Nat Med. 2013. PMID: 23475201 Free PMC article.
32 results