Tuveson DA - Search Results

1

A novel method for quantification of gemcitabine and its metabolites 2',2'-difluorodeoxyuridine and gemcitabine triphosphate in tumour tissue by LC-MS/MS: comparison with (19)F NMR spectroscopy.

Bapiro TE, Richards FM, Goldgraben MA, Olive KP, Madhu B, Frese KK, Cook N, Jacobetz MA, Smith DM, Tuveson DA, Griffiths JR, Jodrell DI. Bapiro TE, et al. Among authors: tuveson da. Cancer Chemother Pharmacol. 2011 Nov;68(5):1243-53. doi: 10.1007/s00280-011-1613-0. Epub 2011 Mar 23. Cancer Chemother Pharmacol. 2011. PMID: 21431415 Free PMC article.

2

Suppression of BRAF(V599E) in human melanoma abrogates transformation.

Hingorani SR, Jacobetz MA, Robertson GP, Herlyn M, Tuveson DA. Hingorani SR, et al. Among authors: tuveson da. Cancer Res. 2003 Sep 1;63(17):5198-202. Cancer Res. 2003. PMID: 14500344

3

Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse.

Hingorani SR, Petricoin EF, Maitra A, Rajapakse V, King C, Jacobetz MA, Ross S, Conrads TP, Veenstra TD, Hitt BA, Kawaguchi Y, Johann D, Liotta LA, Crawford HC, Putt ME, Jacks T, Wright CV, Hruban RH, Lowy AM, Tuveson DA. Hingorani SR, et al. Among authors: tuveson da. Cancer Cell. 2003 Dec;4(6):437-50. doi: 10.1016/s1535-6108(03)00309-x. Cancer Cell. 2003. PMID: 14706336 Free article.

4

Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects.

Tuveson DA, Shaw AT, Willis NA, Silver DP, Jackson EL, Chang S, Mercer KL, Grochow R, Hock H, Crowley D, Hingorani SR, Zaks T, King C, Jacobetz MA, Wang L, Bronson RT, Orkin SH, DePinho RA, Jacks T. Tuveson DA, et al. Cancer Cell. 2004 Apr;5(4):375-87. doi: 10.1016/s1535-6108(04)00085-6. Cancer Cell. 2004. PMID: 15093544 Free article.

5

Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome.

Olive KP, Tuveson DA, Ruhe ZC, Yin B, Willis NA, Bronson RT, Crowley D, Jacks T. Olive KP, et al. Among authors: tuveson da. Cell. 2004 Dec 17;119(6):847-60. doi: 10.1016/j.cell.2004.11.004. Cell. 2004. PMID: 15607980 Free article.

6

Mice expressing a mammary gland-specific R270H mutation in the p53 tumor suppressor gene mimic human breast cancer development.

Wijnhoven SW, Zwart E, Speksnijder EN, Beems RB, Olive KP, Tuveson DA, Jonkers J, Schaap MM, van den Berg J, Jacks T, van Steeg H, de Vries A. Wijnhoven SW, et al. Among authors: tuveson da. Cancer Res. 2005 Sep 15;65(18):8166-73. doi: 10.1158/0008-5472.CAN-05-1650. Cancer Res. 2005. PMID: 16166291

7

The differential effects of mutant p53 alleles on advanced murine lung cancer.

Jackson EL, Olive KP, Tuveson DA, Bronson R, Crowley D, Brown M, Jacks T. Jackson EL, et al. Among authors: tuveson da. Cancer Res. 2005 Nov 15;65(22):10280-8. doi: 10.1158/0008-5472.CAN-05-2193. Cancer Res. 2005. PMID: 16288016

8

The use of targeted mouse models for preclinical testing of novel cancer therapeutics.

Olive KP, Tuveson DA. Olive KP, et al. Among authors: tuveson da. Clin Cancer Res. 2006 Sep 15;12(18):5277-87. doi: 10.1158/1078-0432.CCR-06-0436. Clin Cancer Res. 2006. PMID: 17000660 Review.

9

Maximizing mouse cancer models.

Frese KK, Tuveson DA. Frese KK, et al. Among authors: tuveson da. Nat Rev Cancer. 2007 Sep;7(9):645-58. doi: 10.1038/nrc2192. Nat Rev Cancer. 2007. PMID: 17687385 Review.

10

K-Ras-driven pancreatic cancer mouse model for anticancer inhibitor analyses.

Cook N, Olive KP, Frese K, Tuveson DA. Cook N, et al. Among authors: tuveson da. Methods Enzymol. 2008;439:73-85. doi: 10.1016/S0076-6879(07)00406-5. Methods Enzymol. 2008. PMID: 18374157

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