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Page 1
Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis.
Locasale JW, Grassian AR, Melman T, Lyssiotis CA, Mattaini KR, Bass AJ, Heffron G, Metallo CM, Muranen T, Sharfi H, Sasaki AT, Anastasiou D, Mullarky E, Vokes NI, Sasaki M, Beroukhim R, Stephanopoulos G, Ligon AH, Meyerson M, Richardson AL, Chin L, Wagner G, Asara JM, Brugge JS, Cantley LC, Vander Heiden MG. Locasale JW, et al. Among authors: brugge js. Nat Genet. 2011 Jul 31;43(9):869-74. doi: 10.1038/ng.890. Nat Genet. 2011. PMID: 21804546 Free PMC article.
The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor.
Gozani O, Karuman P, Jones DR, Ivanov D, Cha J, Lugovskoy AA, Baird CL, Zhu H, Field SJ, Lessnick SL, Villasenor J, Mehrotra B, Chen J, Rao VR, Brugge JS, Ferguson CG, Payrastre B, Myszka DG, Cantley LC, Wagner G, Divecha N, Prestwich GD, Yuan J. Gozani O, et al. Among authors: brugge js. Cell. 2003 Jul 11;114(1):99-111. doi: 10.1016/s0092-8674(03)00480-x. Cell. 2003. PMID: 12859901 Free article.
Engineering tumors with 3D scaffolds.
Fischbach C, Chen R, Matsumoto T, Schmelzle T, Brugge JS, Polverini PJ, Mooney DJ. Fischbach C, et al. Among authors: brugge js. Nat Methods. 2007 Oct;4(10):855-60. doi: 10.1038/nmeth1085. Epub 2007 Sep 2. Nat Methods. 2007. PMID: 17767164
A structure-guided approach to creating covalent FGFR inhibitors.
Zhou W, Hur W, McDermott U, Dutt A, Xian W, Ficarro SB, Zhang J, Sharma SV, Brugge J, Meyerson M, Settleman J, Gray NS. Zhou W, et al. Chem Biol. 2010 Mar 26;17(3):285-95. doi: 10.1016/j.chembiol.2010.02.007. Chem Biol. 2010. PMID: 20338520 Free PMC article.
PTK6 regulates IGF-1-induced anchorage-independent survival.
Irie HY, Shrestha Y, Selfors LM, Frye F, Iida N, Wang Z, Zou L, Yao J, Lu Y, Epstein CB, Natesan S, Richardson AL, Polyak K, Mills GB, Hahn WC, Brugge JS. Irie HY, et al. Among authors: brugge js. PLoS One. 2010 Jul 23;5(7):e11729. doi: 10.1371/journal.pone.0011729. PLoS One. 2010. PMID: 20668531 Free PMC article.
270 results