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The hygiene hypothesis does not apply to atopic eczema in childhood.
Cramer C, Link E, Koletzko S, Lehmann I, Heinrich J, Wichmann HE, Bauer CP, V Berg A, Berdel D, Herbarth O, Schaaf B, Borte M, Behrendt H, Krämer U. Cramer C, et al. Among authors: lehmann i. Chem Immunol Allergy. 2012;96:15-23. doi: 10.1159/000331805. Epub 2012 Mar 13. Chem Immunol Allergy. 2012. PMID: 22433366
Elder siblings enhance the effect of filaggrin mutations on childhood eczema: results from the 2 birth cohort studies LISAplus and GINIplus.
Cramer C, Link E, Horster M, Koletzko S, Bauer CP, Berdel D, von Berg A, Lehmann I, Herbarth O, Borte M, Schaaf B, Behrendt H, Chen CM, Sausenthaler S, Illig T, Wichmann HE, Heinrich J, Krämer U; LISAplus Study Group and the GINIplus Study Group. Cramer C, et al. Among authors: lehmann i. J Allergy Clin Immunol. 2010 Jun;125(6):1254-1260.e5. doi: 10.1016/j.jaci.2010.03.036. J Allergy Clin Immunol. 2010. PMID: 20513523
Predictive value of food sensitization and filaggrin mutations in children with eczema.
Filipiak-Pittroff B, Schnopp C, Berdel D, Naumann A, Sedlmeier S, Onken A, Rodriguez E, Fölster-Holst R, Baurecht H, Ollert M, Ring J, Cramer C, von Berg A, Bauer CP, Herbarth O, Lehmann I, Schaaf B, Koletzko S, Wichmann HE, Heinrich J, Weidinger S; GINIplus and LISAplus study groups. Filipiak-Pittroff B, et al. Among authors: lehmann i. J Allergy Clin Immunol. 2011 Dec;128(6):1235-1241.e5. doi: 10.1016/j.jaci.2011.09.014. Epub 2011 Oct 26. J Allergy Clin Immunol. 2011. PMID: 22030464
298 results