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Superenhancer Analysis Defines Novel Epigenomic Subtypes of Non-APL AML, Including an RARα Dependency Targetable by SY-1425, a Potent and Selective RARα Agonist.
McKeown MR, Corces MR, Eaton ML, Fiore C, Lee E, Lopez JT, Chen MW, Smith D, Chan SM, Koenig JL, Austgen K, Guenther MG, Orlando DA, Lovén J, Fritz CC, Majeti R. McKeown MR, et al. Among authors: chen mw. Cancer Discov. 2017 Oct;7(10):1136-1153. doi: 10.1158/2159-8290.CD-17-0399. Epub 2017 Jul 20. Cancer Discov. 2017. PMID: 28729405 Free PMC article.
ΔNp63/p73 drive metastatic colonization by controlling a regenerative epithelial stem cell program in quasi-mesenchymal cancer stem cells.
Lambert AW, Fiore C, Chutake Y, Verhaar ER, Strasser PC, Chen MW, Farouq D, Das S, Li X, Eaton EN, Zhang Y, Liu Donaher J, Engstrom I, Reinhardt F, Yuan B, Gupta S, Wollison B, Eaton M, Bierie B, Carulli J, Olson ER, Guenther MG, Weinberg RA. Lambert AW, et al. Among authors: chen mw. Dev Cell. 2022 Dec 19;57(24):2714-2730.e8. doi: 10.1016/j.devcel.2022.11.015. Dev Cell. 2022. PMID: 36538894 Free PMC article.
423 results