Warman ML - Search Results

1

Mechanotransduction in bone tissue: The A214V and G171V mutations in Lrp5 enhance load-induced osteogenesis in a surface-selective manner.

Niziolek PJ, Warman ML, Robling AG. Niziolek PJ, et al. Among authors: warman ml. Bone. 2012 Sep;51(3):459-65. doi: 10.1016/j.bone.2012.05.023. Epub 2012 Jun 28. Bone. 2012. PMID: 22750014 Free PMC article.

2

An RNA-seq protocol to identify mRNA expression changes in mouse diaphyseal bone: applications in mice with bone property altering Lrp5 mutations.

Ayturk UM, Jacobsen CM, Christodoulou DC, Gorham J, Seidman JG, Seidman CE, Robling AG, Warman ML. Ayturk UM, et al. Among authors: warman ml. J Bone Miner Res. 2013 Oct;28(10):2081-93. doi: 10.1002/jbmr.1946. J Bone Miner Res. 2013. PMID: 23553928 Free PMC article.

3

Sclerostin inhibition reverses skeletal fragility in an Lrp5-deficient mouse model of OPPG syndrome.

Kedlaya R, Veera S, Horan DJ, Moss RE, Ayturk UM, Jacobsen CM, Bowen ME, Paszty C, Warman ML, Robling AG. Kedlaya R, et al. Among authors: warman ml. Sci Transl Med. 2013 Nov 13;5(211):211ra158. doi: 10.1126/scitranslmed.3006627. Sci Transl Med. 2013. PMID: 24225945 Free PMC article.

4

Targeting the LRP5 pathway improves bone properties in a mouse model of osteogenesis imperfecta.

Jacobsen CM, Barber LA, Ayturk UM, Roberts HJ, Deal LE, Schwartz MA, Weis M, Eyre D, Zurakowski D, Robling AG, Warman ML. Jacobsen CM, et al. Among authors: warman ml. J Bone Miner Res. 2014 Oct;29(10):2297-306. doi: 10.1002/jbmr.2198. J Bone Miner Res. 2014. PMID: 24677211 Free PMC article.

5

High Bone Mass-Causing Mutant LRP5 Receptors Are Resistant to Endogenous Inhibitors In Vivo.

Niziolek PJ, MacDonald BT, Kedlaya R, Zhang M, Bellido T, He X, Warman ML, Robling AG. Niziolek PJ, et al. Among authors: warman ml. J Bone Miner Res. 2015 Oct;30(10):1822-30. doi: 10.1002/jbmr.2514. J Bone Miner Res. 2015. PMID: 25808845 Free PMC article.

6

Missense Mutations in LRP5 Associated with High Bone Mass Protect the Mouse Skeleton from Disuse- and Ovariectomy-Induced Osteopenia.

Niziolek PJ, Bullock W, Warman ML, Robling AG. Niziolek PJ, et al. Among authors: warman ml. PLoS One. 2015 Nov 10;10(11):e0140775. doi: 10.1371/journal.pone.0140775. eCollection 2015. PLoS One. 2015. PMID: 26554834 Free PMC article.

7

Enhanced Wnt signaling improves bone mass and strength, but not brittleness, in the Col1a1(+/mov13) mouse model of type I Osteogenesis Imperfecta.

Jacobsen CM, Schwartz MA, Roberts HJ, Lim KE, Spevak L, Boskey AL, Zurakowski D, Robling AG, Warman ML. Jacobsen CM, et al. Among authors: warman ml. Bone. 2016 Sep;90:127-32. doi: 10.1016/j.bone.2016.06.005. Epub 2016 Jun 11. Bone. 2016. PMID: 27297606 Free PMC article.

8

Induction of Lrp5 HBM-causing mutations in Cathepsin-K expressing cells alters bone metabolism.

Kang KS, Hong JM, Horan DJ, Lim KE, Bullock WA, Bruzzaniti A, Hann S, Warman ML, Robling AG. Kang KS, et al. Among authors: warman ml. Bone. 2019 Mar;120:166-175. doi: 10.1016/j.bone.2018.10.007. Epub 2018 Oct 25. Bone. 2019. PMID: 30409757 Free PMC article.

9

Expression of a Degradation-Resistant β-Catenin Mutant in Osteocytes Protects the Skeleton From Mechanodeprivation-Induced Bone Wasting.

Bullock WA, Hoggatt AM, Horan DJ, Lewis KJ, Yokota H, Hann S, Warman ML, Sebastian A, Loots GG, Pavalko FM, Robling AG. Bullock WA, et al. Among authors: warman ml. J Bone Miner Res. 2019 Oct;34(10):1964-1975. doi: 10.1002/jbmr.3812. Epub 2019 Aug 5. J Bone Miner Res. 2019. PMID: 31173667 Free PMC article.

10

Combination therapy in the Col1a2^G610C mouse model of Osteogenesis Imperfecta reveals an additive effect of enhancing LRP5 signaling and inhibiting TGFβ signaling on trabecular bone but not on cortical bone.

Kaupp S, Horan DJ, Lim KE, Feldman HA, Robling AG, Warman ML, Jacobsen CM. Kaupp S, et al. Among authors: warman ml. Bone. 2020 Feb;131:115084. doi: 10.1016/j.bone.2019.115084. Epub 2019 Oct 21. Bone. 2020. PMID: 31648079 Free PMC article.

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