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Endothelial acyl-CoA synthetase 1 is not required for inflammatory and apoptotic effects of a saturated fatty acid-rich environment.
Li X, Gonzalez O, Shen X, Barnhart S, Kramer F, Kanter JE, Vivekanandan-Giri A, Tsuchiya K, Handa P, Pennathur S, Kim F, Coleman RA, Schaffer JE, Bornfeldt KE. Li X, et al. Arterioscler Thromb Vasc Biol. 2013 Feb;33(2):232-40. doi: 10.1161/ATVBAHA.112.252239. Epub 2012 Dec 13. Arterioscler Thromb Vasc Biol. 2013. PMID: 23241406 Free PMC article.
Diabetes promotes an inflammatory macrophage phenotype and atherosclerosis through acyl-CoA synthetase 1.
Kanter JE, Kramer F, Barnhart S, Averill MM, Vivekanandan-Giri A, Vickery T, Li LO, Becker L, Yuan W, Chait A, Braun KR, Potter-Perigo S, Sanda S, Wight TN, Pennathur S, Serhan CN, Heinecke JW, Coleman RA, Bornfeldt KE. Kanter JE, et al. Proc Natl Acad Sci U S A. 2012 Mar 20;109(12):E715-24. doi: 10.1073/pnas.1111600109. Epub 2012 Jan 17. Proc Natl Acad Sci U S A. 2012. PMID: 22308341 Free PMC article.
Inflammatory stimuli induce acyl-CoA thioesterase 7 and remodeling of phospholipids containing unsaturated long (≥C20)-acyl chains in macrophages.
Wall VZ, Barnhart S, Kramer F, Kanter JE, Vivekanandan-Giri A, Pennathur S, Bolego C, Ellis JM, Gijón MA, Wolfgang MJ, Bornfeldt KE. Wall VZ, et al. Among authors: vivekanandan giri a. J Lipid Res. 2017 Jun;58(6):1174-1185. doi: 10.1194/jlr.M076489. Epub 2017 Apr 17. J Lipid Res. 2017. PMID: 28416579 Free PMC article.
Acyl-CoA synthetase 1 is induced by Gram-negative bacteria and lipopolysaccharide and is required for phospholipid turnover in stimulated macrophages.
Rubinow KB, Wall VZ, Nelson J, Mar D, Bomsztyk K, Askari B, Lai MA, Smith KD, Han MS, Vivekanandan-Giri A, Pennathur S, Albert CJ, Ford DA, Davis RJ, Bornfeldt KE. Rubinow KB, et al. J Biol Chem. 2013 Apr 5;288(14):9957-9970. doi: 10.1074/jbc.M113.458372. Epub 2013 Feb 20. J Biol Chem. 2013. PMID: 23426369 Free PMC article.
Testing the role of myeloid cell glucose flux in inflammation and atherosclerosis.
Nishizawa T, Kanter JE, Kramer F, Barnhart S, Shen X, Vivekanandan-Giri A, Wall VZ, Kowitz J, Devaraj S, O'Brien KD, Pennathur S, Tang J, Miyaoka RS, Raines EW, Bornfeldt KE. Nishizawa T, et al. Among authors: vivekanandan giri a. Cell Rep. 2014 Apr 24;7(2):356-365. doi: 10.1016/j.celrep.2014.03.028. Epub 2014 Apr 13. Cell Rep. 2014. PMID: 24726364 Free PMC article.
27 results