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A large-scale evaluation of computational protein function prediction.
Radivojac P, Clark WT, Oron TR, Schnoes AM, Wittkop T, Sokolov A, Graim K, Funk C, Verspoor K, Ben-Hur A, Pandey G, Yunes JM, Talwalkar AS, Repo S, Souza ML, Piovesan D, Casadio R, Wang Z, Cheng J, Fang H, Gough J, Koskinen P, Törönen P, Nokso-Koivisto J, Holm L, Cozzetto D, Buchan DW, Bryson K, Jones DT, Limaye B, Inamdar H, Datta A, Manjari SK, Joshi R, Chitale M, Kihara D, Lisewski AM, Erdin S, Venner E, Lichtarge O, Rentzsch R, Yang H, Romero AE, Bhat P, Paccanaro A, Hamp T, Kaßner R, Seemayer S, Vicedo E, Schaefer C, Achten D, Auer F, Boehm A, Braun T, Hecht M, Heron M, Hönigschmid P, Hopf TA, Kaufmann S, Kiening M, Krompass D, Landerer C, Mahlich Y, Roos M, Björne J, Salakoski T, Wong A, Shatkay H, Gatzmann F, Sommer I, Wass MN, Sternberg MJ, Škunca N, Supek F, Bošnjak M, Panov P, Džeroski S, Šmuc T, Kourmpetis YA, van Dijk AD, ter Braak CJ, Zhou Y, Gong Q, Dong X, Tian W, Falda M, Fontana P, Lavezzo E, Di Camillo B, Toppo S, Lan L, Djuric N, Guo Y, Vucetic S, Bairoch A, Linial M, Babbitt PC, Brenner SE, Orengo C, Rost B, Mooney SD, Friedberg I. Radivojac P, et al. Among authors: schaefer c. Nat Methods. 2013 Mar;10(3):221-7. doi: 10.1038/nmeth.2340. Epub 2013 Jan 27. Nat Methods. 2013. PMID: 23353650 Free PMC article.
Homology-based inference sets the bar high for protein function prediction.
Hamp T, Kassner R, Seemayer S, Vicedo E, Schaefer C, Achten D, Auer F, Boehm A, Braun T, Hecht M, Heron M, Hönigschmid P, Hopf TA, Kaufmann S, Kiening M, Krompass D, Landerer C, Mahlich Y, Roos M, Rost B. Hamp T, et al. Among authors: schaefer c. BMC Bioinformatics. 2013;14 Suppl 3(Suppl 3):S7. doi: 10.1186/1471-2105-14-S3-S7. Epub 2013 Feb 28. BMC Bioinformatics. 2013. PMID: 23514582 Free PMC article.
Protein disorder--a breakthrough invention of evolution?
Schlessinger A, Schaefer C, Vicedo E, Schmidberger M, Punta M, Rost B. Schlessinger A, et al. Among authors: schaefer c. Curr Opin Struct Biol. 2011 Jun;21(3):412-8. doi: 10.1016/j.sbi.2011.03.014. Epub 2011 Apr 20. Curr Opin Struct Biol. 2011. PMID: 21514145 Review.
SNPdbe: constructing an nsSNP functional impacts database.
Schaefer C, Meier A, Rost B, Bromberg Y. Schaefer C, et al. Bioinformatics. 2012 Feb 15;28(4):601-2. doi: 10.1093/bioinformatics/btr705. Epub 2011 Dec 30. Bioinformatics. 2012. PMID: 22210871 Free PMC article.
Statin Initiation and Dementia Incidence in a Large Health Care System From 1997 to 2020: A Target Trial Emulation Study.
Zimmerman SC, Choi M, Jiang C, Ferguson EL, Hoffmann TJ, Swinnerton K, Oni-Orisan A, Gilsanz P, Meyers TJ, Choudhary V, Whitmer RA, Risch N, Krauss RM, Schaefer CA, Glymour MM. Zimmerman SC, et al. Among authors: schaefer ca. Neurology. 2025 Jul 22;105(2):e213855. doi: 10.1212/WNL.0000000000213855. Epub 2025 Jun 27. Neurology. 2025. PMID: 40577672 Free PMC article.
1,224 results