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Reduced Oct4 expression directs a robust pluripotent state with distinct signaling activity and increased enhancer occupancy by Oct4 and Nanog.
Karwacki-Neisius V, Göke J, Osorno R, Halbritter F, Ng JH, Weiße AY, Wong FC, Gagliardi A, Mullin NP, Festuccia N, Colby D, Tomlinson SR, Ng HH, Chambers I. Karwacki-Neisius V, et al. Among authors: festuccia n. Cell Stem Cell. 2013 May 2;12(5):531-45. doi: 10.1016/j.stem.2013.04.023. Cell Stem Cell. 2013. PMID: 23642364 Free PMC article.
Molecular coupling of Tsix regulation and pluripotency.
Navarro P, Oldfield A, Legoupi J, Festuccia N, Dubois A, Attia M, Schoorlemmer J, Rougeulle C, Chambers I, Avner P. Navarro P, et al. Among authors: festuccia n. Nature. 2010 Nov 18;468(7322):457-60. doi: 10.1038/nature09496. Nature. 2010. PMID: 21085182
The pluripotent genome in three dimensions is shaped around pluripotency factors.
de Wit E, Bouwman BA, Zhu Y, Klous P, Splinter E, Verstegen MJ, Krijger PH, Festuccia N, Nora EP, Welling M, Heard E, Geijsen N, Poot RA, Chambers I, de Laat W. de Wit E, et al. Among authors: festuccia n. Nature. 2013 Sep 12;501(7466):227-31. doi: 10.1038/nature12420. Epub 2013 Jul 24. Nature. 2013. PMID: 23883933
Esrrb Complementation Rescues Development of Nanog-Null Germ Cells.
Zhang M, Leitch HG, Tang WWC, Festuccia N, Hall-Ponsele E, Nichols J, Surani MA, Smith A, Chambers I. Zhang M, et al. Among authors: festuccia n. Cell Rep. 2018 Jan 9;22(2):332-339. doi: 10.1016/j.celrep.2017.12.060. Cell Rep. 2018. PMID: 29320730 Free PMC article.
21 results