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Reduced Oct4 expression directs a robust pluripotent state with distinct signaling activity and increased enhancer occupancy by Oct4 and Nanog.
Karwacki-Neisius V, Göke J, Osorno R, Halbritter F, Ng JH, Weiße AY, Wong FC, Gagliardi A, Mullin NP, Festuccia N, Colby D, Tomlinson SR, Ng HH, Chambers I. Karwacki-Neisius V, et al. Among authors: mullin np. Cell Stem Cell. 2013 May 2;12(5):531-45. doi: 10.1016/j.stem.2013.04.023. Cell Stem Cell. 2013. PMID: 23642364 Free PMC article.
An Oct4-centered protein interaction network in embryonic stem cells.
van den Berg DLC, Snoek T, Mullin NP, Yates A, Bezstarosti K, Demmers J, Chambers I, Poot RA. van den Berg DLC, et al. Among authors: mullin np. Cell Stem Cell. 2010 Apr 2;6(4):369-381. doi: 10.1016/j.stem.2010.02.014. Cell Stem Cell. 2010. PMID: 20362541 Free PMC article.
The pluripotency rheostat Nanog functions as a dimer.
Mullin NP, Yates A, Rowe AJ, Nijmeijer B, Colby D, Barlow PN, Walkinshaw MD, Chambers I. Mullin NP, et al. Biochem J. 2008 Apr 15;411(2):227-31. doi: 10.1042/BJ20080134. Biochem J. 2008. PMID: 18290762
Distinct SoxB1 networks are required for naïve and primed pluripotency.
Corsinotti A, Wong FC, Tatar T, Szczerbinska I, Halbritter F, Colby D, Gogolok S, Pantier R, Liggat K, Mirfazeli ES, Hall-Ponsele E, Mullin NP, Wilson V, Chambers I. Corsinotti A, et al. Among authors: mullin np. Elife. 2017 Dec 19;6:e27746. doi: 10.7554/eLife.27746. Elife. 2017. PMID: 29256862 Free PMC article.
24 results