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Classical transient receptor potential channel 1 in hypoxia-induced pulmonary hypertension.
Malczyk M, Veith C, Fuchs B, Hofmann K, Storch U, Schermuly RT, Witzenrath M, Ahlbrecht K, Fecher-Trost C, Flockerzi V, Ghofrani HA, Grimminger F, Seeger W, Gudermann T, Dietrich A, Weissmann N. Malczyk M, et al. Among authors: flockerzi v. Am J Respir Crit Care Med. 2013 Dec 15;188(12):1451-9. doi: 10.1164/rccm.201307-1252OC. Am J Respir Crit Care Med. 2013. PMID: 24251695
Store-operated Ca2+ current and TRPV6 channels in lymph node prostate cancer cells.
Bödding M, Fecher-Trost C, Flockerzi V. Bödding M, et al. Among authors: flockerzi v. J Biol Chem. 2003 Dec 19;278(51):50872-9. doi: 10.1074/jbc.M308800200. Epub 2003 Oct 8. J Biol Chem. 2003. PMID: 14534305 Free article.
These properties are also shared by the Ca2+-sensing Ca2+ current (ITRPV6) recorded after heterologous expression of TRPV6 cDNA in human embryonic kidney and rat basophilic leukemia cells (Bodding, M., Wissenbach, U., Flockerzi, V. (2002) J. Biol. Chem. 277, 36656-3 …
These properties are also shared by the Ca2+-sensing Ca2+ current (ITRPV6) recorded after heterologous expression of TRPV6 cDNA in human emb …
TRP channels as new pharmacological targets.
Gudermann T, Flockerzi V. Gudermann T, et al. Among authors: flockerzi v. Naunyn Schmiedebergs Arch Pharmacol. 2005 Apr;371(4):241-4. doi: 10.1007/s00210-005-1029-7. Naunyn Schmiedebergs Arch Pharmacol. 2005. PMID: 15756597 No abstract available.
TRPC3 channels are required for synaptic transmission and motor coordination.
Hartmann J, Dragicevic E, Adelsberger H, Henning HA, Sumser M, Abramowitz J, Blum R, Dietrich A, Freichel M, Flockerzi V, Birnbaumer L, Konnerth A. Hartmann J, et al. Among authors: flockerzi v. Neuron. 2008 Aug 14;59(3):392-8. doi: 10.1016/j.neuron.2008.06.009. Neuron. 2008. PMID: 18701065 Free PMC article.
The Ca(2+) sensor stromal interaction molecule 1 (STIM1) is necessary and sufficient for the store-operated Ca(2+) entry function of transient receptor potential canonical (TRPC) 1 and 4 channels in endothelial cells.
Sundivakkam PC, Freichel M, Singh V, Yuan JP, Vogel SM, Flockerzi V, Malik AB, Tiruppathi C. Sundivakkam PC, et al. Among authors: flockerzi v. Mol Pharmacol. 2012 Apr;81(4):510-26. doi: 10.1124/mol.111.074658. Epub 2011 Dec 30. Mol Pharmacol. 2012. PMID: 22210847 Free PMC article.
Lung endothelial Ca2+ and permeability response to platelet-activating factor is mediated by acid sphingomyelinase and transient receptor potential classical 6.
Samapati R, Yang Y, Yin J, Stoerger C, Arenz C, Dietrich A, Gudermann T, Adam D, Wu S, Freichel M, Flockerzi V, Uhlig S, Kuebler WM. Samapati R, et al. Among authors: flockerzi v. Am J Respir Crit Care Med. 2012 Jan 15;185(2):160-70. doi: 10.1164/rccm.201104-0717OC. Am J Respir Crit Care Med. 2012. PMID: 22246702
The in vivo TRPV6 protein starts at a non-AUG triplet, decoded as methionine, upstream of canonical initiation at AUG.
Fecher-Trost C, Wissenbach U, Beck A, Schalkowsky P, Stoerger C, Doerr J, Dembek A, Simon-Thomas M, Weber A, Wollenberg P, Ruppert T, Middendorff R, Maurer HH, Flockerzi V. Fecher-Trost C, et al. Among authors: flockerzi v. J Biol Chem. 2013 Jun 7;288(23):16629-16644. doi: 10.1074/jbc.M113.469726. Epub 2013 Apr 23. J Biol Chem. 2013. PMID: 23612980 Free PMC article. Clinical Trial.
258 results