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A novel approach to rapidly prevent age-related cognitive decline.
Adlard PA, Sedjahtera A, Gunawan L, Bray L, Hare D, Lear J, Doble P, Bush AI, Finkelstein DI, Cherny RA. Adlard PA, et al. Among authors: cherny ra. Aging Cell. 2014 Apr;13(2):351-9. doi: 10.1111/acel.12178. Epub 2013 Dec 4. Aging Cell. 2014. PMID: 24305557 Free PMC article.
Targeting metals rescues the phenotype in an animal model of tauopathy.
Sedjahtera A, Gunawan L, Bray L, Hung LW, Parsons J, Okamura N, Villemagne VL, Yanai K, Liu XM, Chan J, Bush AI, Finkelstein DI, Barnham KJ, Cherny RA, Adlard PA. Sedjahtera A, et al. Among authors: cherny ra. Metallomics. 2018 Sep 19;10(9):1339-1347. doi: 10.1039/c8mt00153g. Metallomics. 2018. PMID: 30168573
Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial Abeta.
Adlard PA, Cherny RA, Finkelstein DI, Gautier E, Robb E, Cortes M, Volitakis I, Liu X, Smith JP, Perez K, Laughton K, Li QX, Charman SA, Nicolazzo JA, Wilkins S, Deleva K, Lynch T, Kok G, Ritchie CW, Tanzi RE, Cappai R, Masters CL, Barnham KJ, Bush AI. Adlard PA, et al. Among authors: cherny ra. Neuron. 2008 Jul 10;59(1):43-55. doi: 10.1016/j.neuron.2008.06.018. Neuron. 2008. PMID: 18614028 Free article.
The effect of dopamine on MPTP-induced rotarod disability.
Ayton S, George JL, Adlard PA, Bush AI, Cherny RA, Finkelstein DI. Ayton S, et al. Among authors: cherny ra. Neurosci Lett. 2013 May 24;543:105-9. doi: 10.1016/j.neulet.2013.02.066. Epub 2013 Apr 2. Neurosci Lett. 2013. PMID: 23562518
The novel compound PBT434 prevents iron mediated neurodegeneration and alpha-synuclein toxicity in multiple models of Parkinson's disease.
Finkelstein DI, Billings JL, Adlard PA, Ayton S, Sedjahtera A, Masters CL, Wilkins S, Shackleford DM, Charman SA, Bal W, Zawisza IA, Kurowska E, Gundlach AL, Ma S, Bush AI, Hare DJ, Doble PA, Crawford S, Gautier EC, Parsons J, Huggins P, Barnham KJ, Cherny RA. Finkelstein DI, et al. Among authors: cherny ra. Acta Neuropathol Commun. 2017 Jun 28;5(1):53. doi: 10.1186/s40478-017-0456-2. Acta Neuropathol Commun. 2017. PMID: 28659169 Free PMC article.
92 results