Zheng G - Search Results

1

Molecular dynamics guided design of tocoflexol: a new radioprotectant tocotrienol with enhanced bioavailability.

Compadre CM, Singh A, Thakkar S, Zheng G, Breen PJ, Ghosh S, Kiaei M, Boerma M, Varughese KI, Hauer-Jensen M. Compadre CM, et al. Among authors: zheng g. Drug Dev Res. 2014 Feb;75(1):10-22. doi: 10.1002/ddr.21162. Epub 2013 Dec 26. Drug Dev Res. 2014. PMID: 24648045 Free PMC article.

2

Synthesis of (2R,8' S,3' E)-δ-tocodienol, a tocoflexol family member designed to have a superior pharmacokinetic profile compared to δ-tocotrienol.

Liu X, Gujarathi S, Zhang X, Shao L, Boerma M, Compadre CM, Crooks PA, Hauer-Jensen M, Zhou D, Zheng G. Liu X, et al. Among authors: zheng g. Tetrahedron. 2016 Jul;72(27-28):4001-4006. doi: 10.1016/j.tet.2016.05.028. Epub 2016 May 12. Tetrahedron. 2016. PMID: 27773949 Free PMC article.

3

Deuteration of the farnesyl terminal methyl groups of δ-tocotrienol and its effects on the metabolic stability and ability of inducing G-CSF production.

Liu X, Gao Z, Fu Q, Song L, Zhang P, Zhang X, Hendrickson H, Crooks PA, Zhou D, Zheng G. Liu X, et al. Among authors: zheng g. Bioorg Med Chem. 2020 Jun 1;28(11):115498. doi: 10.1016/j.bmc.2020.115498. Epub 2020 Apr 8. Bioorg Med Chem. 2020. PMID: 32291146 Free PMC article.

4

Mitigation of late cardiovascular effects of oxygen ion radiation by γ-tocotrienol in a mouse model.

Nemec-Bakk AS, Sridharan V, Landes RD, Singh P, Cao M, Seawright JW, Liu X, Zheng G, Dominic P, Pathak R, Boerma M. Nemec-Bakk AS, et al. Among authors: zheng g. Life Sci Space Res (Amst). 2021 Nov;31:43-50. doi: 10.1016/j.lssr.2021.07.006. Epub 2021 Aug 3. Life Sci Space Res (Amst). 2021. PMID: 34689949 Free PMC article.

5

1,4-Diphenalkylpiperidines: A new scaffold for the design of potent inhibitors of the vesicular monoamine transporter-2.

Nickell JR, Culver JP, Janganati V, Zheng G, Dwoskin LP, Crooks PA. Nickell JR, et al. Among authors: zheng g. Bioorg Med Chem Lett. 2016 Jul 1;26(13):2997-3000. doi: 10.1016/j.bmcl.2016.05.025. Epub 2016 May 10. Bioorg Med Chem Lett. 2016. PMID: 27212067 Free PMC article.

6

Synthesis and Liver Microsomal Metabolic Stability Studies of a Fluorine-Substituted δ-Tocotrienol Derivative.

Liu X, Poddar S, Song L, Hendrickson H, Zhang X, Yuan Y, Zhou D, Zheng G. Liu X, et al. Among authors: zheng g. ChemMedChem. 2020 Mar 18;15(6):506-516. doi: 10.1002/cmdc.201900676. Epub 2020 Feb 11. ChemMedChem. 2020. PMID: 31957223 Free PMC article.

7

Structural modifications to tetrahydropyridine-3-carboxylate esters en route to the discovery of M5-preferring muscarinic receptor orthosteric antagonists.

Zheng G, Smith AM, Huang X, Subramanian KL, Siripurapu KB, Deaciuc A, Zhan CG, Dwoskin LP. Zheng G, et al. J Med Chem. 2013 Feb 28;56(4):1693-703. doi: 10.1021/jm301774u. Epub 2013 Feb 18. J Med Chem. 2013. PMID: 23379472 Free PMC article.

8

Exploring the effect of N-substitution in nor-lobelane on the interaction with VMAT2: discovery of a potential clinical candidate for treatment of methamphetamine abuse.

Zheng G, Horton DB, Penthala NR, Nickell JR, Culver JP, Deaciuc AG, Dwoskin LP, Crooks PA. Zheng G, et al. Medchemcomm. 2013 Mar;4(3):564-568. doi: 10.1039/C3MD20374C. Medchemcomm. 2013. PMID: 23527317 Free PMC article.

9

An improved model of ethanol and nicotine co-use in female P rats: Effects of naltrexone, varenicline, and the selective nicotinic α6β2* antagonist r-bPiDI.

Maggio SE, Saunders MA, Nixon K, Prendergast MA, Zheng G, Crooks PA, Dwoskin LP, Bell RL, Bardo MT. Maggio SE, et al. Among authors: zheng g. Drug Alcohol Depend. 2018 Dec 1;193:154-161. doi: 10.1016/j.drugalcdep.2018.09.008. Epub 2018 Oct 17. Drug Alcohol Depend. 2018. PMID: 30384323 Free PMC article.

10

A Facile Semisynthesis and Evaluation of Garcinoic Acid and Its Analogs for the Inhibition of Human DNA Polymerase β.

Gujarathi S, Zafar MK, Liu X, Eoff RL, Zheng G. Gujarathi S, et al. Among authors: zheng g. Molecules. 2020 Dec 11;25(24):5847. doi: 10.3390/molecules25245847. Molecules. 2020. PMID: 33322249 Free PMC article.

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