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Secreted amyloid-β precursor protein functions as a GABABR1a ligand to modulate synaptic transmission.
Rice HC, de Malmazet D, Schreurs A, Frere S, Van Molle I, Volkov AN, Creemers E, Vertkin I, Nys J, Ranaivoson FM, Comoletti D, Savas JN, Remaut H, Balschun D, Wierda KD, Slutsky I, Farrow K, De Strooper B, de Wit J. Rice HC, et al. Among authors: comoletti d. Science. 2019 Jan 11;363(6423):eaao4827. doi: 10.1126/science.aao4827. Science. 2019. PMID: 30630900 Free PMC article.
Shed CNTNAP2 ectodomain is detectable in CSF and regulates Ca2+ homeostasis and network synchrony via PMCA2/ATP2B2.
Martín-de-Saavedra MD, Dos Santos M, Culotta L, Varea O, Spielman BP, Parnell E, Forrest MP, Gao R, Yoon S, McCoig E, Jalloul HA, Myczek K, Khalatyan N, Hall EA, Turk LS, Sanz-Clemente A, Comoletti D, Lichtenthaler SF, Burgdorf JS, Barbolina MV, Savas JN, Penzes P. Martín-de-Saavedra MD, et al. Among authors: comoletti d. Neuron. 2022 Feb 16;110(4):627-643.e9. doi: 10.1016/j.neuron.2021.11.025. Epub 2021 Dec 17. Neuron. 2022. PMID: 34921780 Free PMC article.
An ELISA-Based Screening Platform for Ligand-Receptor Discovery.
Ozgul S, von Daake S, Kakehi S, Sereni D, Denissova N, Hanlon C, Huang YJ, Everett JK, Yin C, Montelione GT, Comoletti D. Ozgul S, et al. Among authors: comoletti d. Methods Enzymol. 2019;615:453-475. doi: 10.1016/bs.mie.2018.10.001. Epub 2018 Dec 28. Methods Enzymol. 2019. PMID: 30638538
Super-complexes of adhesion GPCRs and neural guidance receptors.
Jackson VA, Mehmood S, Chavent M, Roversi P, Carrasquero M, Del Toro D, Seyit-Bremer G, Ranaivoson FM, Comoletti D, Sansom MS, Robinson CV, Klein R, Seiradake E. Jackson VA, et al. Among authors: comoletti d. Nat Commun. 2016 Apr 19;7:11184. doi: 10.1038/ncomms11184. Nat Commun. 2016. PMID: 27091502 Free PMC article.
62 results