Bagdany M - Search Results

1

Some gating potentiators, including VX-770, diminish ΔF508-CFTR functional expression.

Veit G, Avramescu RG, Perdomo D, Phuan PW, Bagdany M, Apaja PM, Borot F, Szollosi D, Wu YS, Finkbeiner WE, Hegedus T, Verkman AS, Lukacs GL. Veit G, et al. Among authors: bagdany m. Sci Transl Med. 2014 Jul 23;6(246):246ra97. doi: 10.1126/scitranslmed.3008889. Sci Transl Med. 2014. PMID: 25101887 Free PMC article.

2

Mechanism-based corrector combination restores ΔF508-CFTR folding and function.

Okiyoneda T, Veit G, Dekkers JF, Bagdany M, Soya N, Xu H, Roldan A, Verkman AS, Kurth M, Simon A, Hegedus T, Beekman JM, Lukacs GL. Okiyoneda T, et al. Among authors: bagdany m. Nat Chem Biol. 2013 Jul;9(7):444-54. doi: 10.1038/nchembio.1253. Epub 2013 May 12. Nat Chem Biol. 2013. PMID: 23666117 Free PMC article.

3

Chaperones rescue the energetic landscape of mutant CFTR at single molecule and in cell.

Bagdany M, Veit G, Fukuda R, Avramescu RG, Okiyoneda T, Baaklini I, Singh J, Sovak G, Xu H, Apaja PM, Sattin S, Beitel LK, Roldan A, Colombo G, Balch W, Young JC, Lukacs GL. Bagdany M, et al. Nat Commun. 2017 Aug 30;8(1):398. doi: 10.1038/s41467-017-00444-4. Nat Commun. 2017. PMID: 28855508 Free PMC article.

4

Mutation-specific dual potentiators maximize rescue of CFTR gating mutants.

Veit G, Da Fonte DF, Avramescu RG, Premchandar A, Bagdany M, Xu H, Bensinger D, Stubba D, Schmidt B, Matouk E, Lukacs GL. Veit G, et al. Among authors: bagdany m. J Cyst Fibros. 2020 Mar;19(2):236-244. doi: 10.1016/j.jcf.2019.10.011. Epub 2019 Oct 31. J Cyst Fibros. 2020. PMID: 31678009 Free PMC article.

5

Revisiting the role of cystic fibrosis transmembrane conductance regulator and counterion permeability in the pH regulation of endocytic organelles.

Barriere H, Bagdany M, Bossard F, Okiyoneda T, Wojewodka G, Gruenert D, Radzioch D, Lukacs GL. Barriere H, et al. Among authors: bagdany m. Mol Biol Cell. 2009 Jul;20(13):3125-41. doi: 10.1091/mbc.e09-01-0061. Epub 2009 May 6. Mol Biol Cell. 2009. PMID: 19420138 Free PMC article.

6

Peripheral protein quality control removes unfolded CFTR from the plasma membrane.

Okiyoneda T, Barrière H, Bagdány M, Rabeh WM, Du K, Höhfeld J, Young JC, Lukacs GL. Okiyoneda T, et al. Among authors: bagdany m. Science. 2010 Aug 13;329(5993):805-10. doi: 10.1126/science.1191542. Epub 2010 Jul 1. Science. 2010. PMID: 20595578 Free PMC article.

7

Correction of both NBD1 energetics and domain interface is required to restore ΔF508 CFTR folding and function.

Rabeh WM, Bossard F, Xu H, Okiyoneda T, Bagdany M, Mulvihill CM, Du K, di Bernardo S, Liu Y, Konermann L, Roldan A, Lukacs GL. Rabeh WM, et al. Among authors: bagdany m. Cell. 2012 Jan 20;148(1-2):150-63. doi: 10.1016/j.cell.2011.11.024. Cell. 2012. PMID: 22265408 Free PMC article.

8

Structure-guided combination therapy to potently improve the function of mutant CFTRs.

Veit G, Xu H, Dreano E, Avramescu RG, Bagdany M, Beitel LK, Roldan A, Hancock MA, Lay C, Li W, Morin K, Gao S, Mak PA, Ainscow E, Orth AP, McNamara P, Edelman A, Frenkiel S, Matouk E, Sermet-Gaudelus I, Barnes WG, Lukacs GL. Veit G, et al. Among authors: bagdany m. Nat Med. 2018 Nov;24(11):1732-1742. doi: 10.1038/s41591-018-0200-x. Epub 2018 Oct 8. Nat Med. 2018. PMID: 30297908 Free PMC article.

9

Phosphorylation-dependent modulation of CFTR macromolecular signalling complex activity by cigarette smoke condensate in airway epithelia.

Schnúr A, Premchandar A, Bagdany M, Lukacs GL. Schnúr A, et al. Among authors: bagdany m. Sci Rep. 2019 Sep 3;9(1):12706. doi: 10.1038/s41598-019-48971-y. Sci Rep. 2019. PMID: 31481727 Free PMC article.

10

Depolarized FRET (depolFRET) on the cell surface: FRET control by photoselection.

Bene L, Gogolák P, Ungvári T, Bagdány M, Nagy I, Damjanovich L. Bene L, et al. Among authors: bagdany m. Biochim Biophys Acta. 2016 Feb;1863(2):322-34. doi: 10.1016/j.bbamcr.2015.12.003. Epub 2015 Dec 3. Biochim Biophys Acta. 2016. PMID: 26657258 Free article.

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